64241-34-5 Usage
Description
HYDRAZINECARBOXYLIC ACID, 2-[6-[ETHYL(2-HYDROXYPROPYL)AMINO]-3-PYRIDAZINYL]-, ETHYL ESTER is a complex organic compound with a hydrazinecarboxylic acid core, featuring a 3-pyridazinyl group at the 2-position and an ethyl ester group. The molecule also contains an ethyl(2-hydroxypropyl)amino substituent, which may contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
HYDRAZINECARBOXYLIC ACID, 2-[6-[ETHYL(2-HYDROXYPROPYL)AMINO]-3-PYRIDAZINYL]-, ETHYL ESTER is used as a vasodilatory antihypertensive agent for the management of hypertension. It is considered to be better-tolerated and longer-acting than traditional hydralazine, making it a valuable second-line treatment option.
Used in Drug Development:
The unique structure of HYDRAZINECARBOXYLIC ACID, 2-[6-[ETHYL(2-HYDROXYPROPYL)AMINO]-3-PYRIDAZINYL]-, ETHYL ESTER may also be utilized in the development of new drugs targeting various therapeutic areas. Its ethyl ester and hydrazinecarboxylic acid functionalities, along with the presence of the 3-pyridazinyl and ethyl(2-hydroxypropyl)amino groups, could provide a basis for the design of novel pharmaceutical agents with improved efficacy and safety profiles.
Originator
ISF;（Smith Mine) (Italy)
World Health Organization (WHO)
Cadralazine, a peripheral vasodilator, was introduced in 1989 for
the treatment of arterial hypertension.In 1992, its association with serious side
effects led to the refusal of registration in Norway. Animal experiments have
demonstrated drug-related impairment of thyroid function as well as potential carcinogenicity and genotoxicity. It remains available for treatment of hypertension
in Italy.
Check Digit Verification of cas no
The CAS Registry Mumber 64241-34-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,2,4 and 1 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 64241-34:
(7*6)+(6*4)+(5*2)+(4*4)+(3*1)+(2*3)+(1*4)=105
105 % 10 = 5
So 64241-34-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H21N5O3/c1-4-17(8-9(3)18)11-7-6-10(13-15-11)14-16-12(19)20-5-2/h6-7,9,18H,4-5,8H2,1-3H3,(H,13,14)(H,16,19)
