64244-24-2Relevant academic research and scientific papers
Photocatalytic Reductive Formation of α-Tertiary Ethers from Ketals
Rossolini, Thomas,Ferko, Branislav,Dixon, Darren J.
supporting information, p. 6668 - 6673 (2019/09/03)
A general photocatalytic reductive strategy for the construction of unsymmetrical α-tertiary dialkyl ethers is reported. By merging Lewis acid-mediated ketal activation and visible-light photocatalytic reduction, in situ-generated α-alkoxy radicals were found to engage in addition reactions with a variety of olefinic partners. Good reaction efficiency is demonstrated with a range of ketals of aromatic and aliphatic ketones. Extension to acetal substrates is also described, demonstrating the overall synthetic utility of this methodology for complex ether synthesis.
Formation of Acetals and Ketals from Carbonyl Compounds: A New and Highly Efficient Method Inspired by Cationic Palladium
Green, Shawn D.,Kindoll, Tyler,Lazaro-Martinez, Brenda,Mensah, Enoch A.,West, Jesse
, p. 1810 - 1814 (2019/09/09)
The development of a new, highly efficient, and simple method for masking carbonyl groups as acetals and ketals is described. This methodology relies on the nature of the palladium catalyst to direct the acetalization/ketalization reaction. This new protocol is mild and proceed with a very low catalyst loading at ambient temperatures. The method has been extended to a wide variety of different carbonyl compounds with various steric encumbrances to form the corresponding acetals and ketals in excellent yields.
Rearrangement of Hydroxylated Pinene Derivatives to Fenchone-Type Frameworks: Computational Evidence for Dynamically-Controlled Selectivity
Blümel, Marcus,Nagasawa, Shota,Blackford, Katherine,Hare, Stephanie R.,Tantillo, Dean J.,Sarpong, Richmond
supporting information, p. 9291 - 9298 (2018/07/15)
An acid-catalyzed Prins/semipinacol rearrangement cascade reaction of hydroxylated pinene derivatives that leads to tricyclic fenchone-type scaffolds in very high yields and diastereoselectivity has been developed. Quantum chemical analysis of the selecti
Synthesis and structures of heterobimetallic Ir2M (M=Pd, Pt) sulfido clusters and their catalytic activity for regioselective addition of alcohols to internal 1-aryl-1-alkynes
Masui, Dai,Kochi, Takuya,Tang, Zhen,Ishii, Youichi,Mizobe, Yasushi,Hidai, Masanobu
, p. 69 - 79 (2007/10/03)
The heterobimetallic trinuclear suffido clusters [(Cp*Ir)2(μ3-S)2MCl2] (M = Pd (3), Pt (4); Cp* = η5-C5Me5) were synthesized from the dinuclear hydrogensulfido complex [Cp*IrCl(μ
Nucleophilic cleavage of acetals using organometallic reagents
Mori, Atsunori,Fujiwara, Junya,Maruoka, Keiji,Yamamoto, Hisashi
, p. 83 - 94 (2007/10/02)
A highly chemo- and stereo-selective cleavage of acetals derived from (-)(2R,4R)-2,4-pentanediol with organoaluminum and organotitanium reagents has been demonstrated. The reactions proceed under mild conditions with excellent yields and high chemoselectivities to give, after removal of the auxiliary, chiral alcohols of high enantiomeric purities.
