642474-94-0Relevant academic research and scientific papers
Synthesis, Structure, and Spectroscopic Properties of Isotianil as a Bactericide
Ji, J.,Jia, A.-Q.,Wang, B.,Zhang, J.,Zhang, Q.-F.
, p. 1801 - 1805 (2020/12/01)
Abstract: Isotianil [N-(2-cyanophenyl)-3,4-dichloro-1,2-thiazole-5-carboxamide] has beensynthesized in a good yield with high purity by reaction of the key intermediateproduct, N-(2-carbamoylphenyl)-3,4-dichloro-1,2-thiazole-5-carboxamide, withthionyl chloride in N,N-dimethylformamide at 60°C. The structure of isotianil wasstudied by X-ray analysis. It crystallized in triclinic space group P1 with a =11.459(3), b = 12.632(3), c = 22.528(5) ?, α = 78.897(3), β = 81.730(3), γ =71.493(3)°, Z = 10.
METHOD FOR PRODUCING 3,4-DICHLORO-N-(2-CYANO-PHENYL)-5-ISOTHIAZOLE CARBOXAMIDE
-
Page/Page column 7, (2008/06/13)
The invention relates to a novel method for producing 3,4-dichloro-N-(2-cyano-phenyl)-5-isothiazole carboxamide. According to said method, a) 3,4-dichloro-isothiazole-5-carboxylic acid chloride is reacted with anthranilic acid amide in the presence of an acid acceptor and an aprotic diluent, and b) the N-[2-(aminocarbonyl)-phenyl]-3,4-dichloro-5-isothiazole carboxamide obtained is reacted with a dehydration agent optionally in the presence of an additional diluent. The N-[2-(aminocarbonyl)-phenyl]-3,4-dichloro-5-isothiazole carboxamide is novel.
