224049-04-1

Basic information

• Product Name: Isotianil
• Synonyms: 3,4-Dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide
• CAS NO: 224049-04-1
• Molecular Formula: C₁₁H₅Cl₂N₃OS
• Molecular Weight: 298.1479
• Mol File: 224049-04-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 322.771°C at 760 mmHg
• Flash Point: 149.007°C
• Appearance: /
• Density: 1.6g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.675
• PKA: 9.15±0.70(Predicted)
• CAS DataBase Reference: Isotianil(CAS DataBase Reference)
• NIST Chemistry Reference: Isotianil(224049-04-1)
• EPA Substance Registry System: Isotianil(224049-04-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36-43
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 224049-04-1(Hazardous Substances Data)

Usage

Definition

ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3,4-dichloro-1,2-thiazole-5-carboxylic acid with o-cyanoaniline. It is a fungicide used for the control of rice blast.

InChI:InChI=1/C11H5Cl2N3OS/c12-8-9(18-16-10(8)13)11(17)15-7-4-2-1-3-6(7)5-14/h1-4H,(H,15,17)

Upstream product

• 56914-82-0 3,4-dichloro-isothiazole-5-carbonyl chloride 
• 1885-29-6 anthranilic acid nitrile 
• 28144-70-9 anthranilic acid amide 
• 118-48-9 isatoic anhydride 
• 642474-94-0 N-(2-carbamoylphenyl)-3,4-dichloro-1,2-thiazole-5-carboxamide 

Relevant articles and documents

METHOD FOR PRODUCING 3,4-DICHLORO-N-(2-CYANOPHENYL)-5-ISOTHIAZOLECARBOXAMIDE

The present invention relates to a novel, one-stage method for preparing and isolating 3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide (isotianil), which has microbicidal and plant-fortifying (host defence inducer) properties. In the method accord

PROCESS FOR PREPARING 3,4-DICHLORO-N-(2-CYANOPHENYL)-5-ISOTHIAZOLECARBOXAMIDE

The present invention relates to a novel process for preparing and isolating 3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide (Isotianil), which can be used as an active compound with microbicidal properties, wherein the amount of waste materials - e.g. solvents and diluents - is significantly reduced and the process meets the requirements of industrial scale production, in particular that it provides the product in high yield, high purity, i.e. minimum amount of by-products and impurities, and can be carried out with tolerable corrosivity in industrial scale metal, in particular stainless steel, vessels or Cr-Ni-Mo alloy pressure filters or centrifuges.

METHOD FOR PRODUCING 3,4-DICHLORO-N-(2-CYANO-PHENYL)-5-ISOTHIAZOLE CARBOXAMIDE

The invention relates to a novel one-pot method for producing 3,4-dichloro-N-(2-cyano-phenyl)-5-isothiazole carboxamide. According to said method, a) isatoic acid anhydride is reacted with ammonia gas in the presence of dimethylformamide, b) the anthranil