64248-61-9

Basic information

• Product Name: 2,4-Difluorobenzotrifluoride
• Synonyms: 2,4-DIFLUOROBENZOTRIFLUOROIDE;2,4-Difluoro-1-(trifluoromethyl)benzene;2,4-Difluoro-1-(trifluoromethyl)benzene, alpha,alpha,alpha,2,4-Pentafluorotoluene;2,4-DIFLUOROBENZOTRIFLUORIDE
• CAS NO: 64248-61-9
• Molecular Formula: C₇H₃F₅
• Molecular Weight: 182.09
• Mol File: 64248-61-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 109.081 °C at 760 mmHg
• Flash Point: 27.021 °C
• Appearance: /
• Density: 1.386 g/cm³
• CAS DataBase Reference: 2,4-Difluorobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Difluorobenzotrifluoride(64248-61-9)
• EPA Substance Registry System: 2,4-Difluorobenzotrifluoride(64248-61-9)

Safety Data

• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39
• RIDADR: 1993
• Hazardous Substances Data: 64248-61-9(Hazardous Substances Data)

Usage

General Description

2,4-Difluorobenzotrifluoride, also known as 2,4-DFBT, is a chemical compound with the molecular formula C7H3F5. It is a colorless liquid with a faint odor and is primarily used as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. 2,4-DFBT is also used as a solvent in various industrial processes and as a reagent in organic synthesis. It is important to handle this chemical with care as it is flammable and may cause irritation to the skin, eyes, and respiratory system upon contact. It is important to follow proper safety precautions when handling and storing 2,4-Difluorobenzotrifluoride to avoid any potential hazards.

Upstream product

• 1583-58-0 2,4-difluoro-benzoic acid 
• 288101-48-4 2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane 
• 1643-19-2 tetrabutylammomium bromide 
• 77152-08-0 trifluoromethylcopper(I) 
• 144025-03-6 2,4-difluorophenylboronic acid 
• 115812-34-5 2,4-difluoro-5-chlorobenzotrifluoride 

Downstream Products

• 952233-11-3 (5-Fluoro-2-trifluoromethyl-phenyl)-hydrazine hydrochloride 
• 1233541-64-4 C₉H₈F₄O 
• 1233541-58-6 C₉H₈F₄O 
• 1048921-49-8 2,6-difluoro-3-(trifluoromethyl)benzoic acid 

Relevant articles and documents

C(sp2)-CF3Reductive Elimination from Well-Defined Argentate(III) Complexes [nBu4N][Ag(Ar)(CF3)3]

The preparation of a series of well-defined, shelf-stable square planar aryl(tris(trifluoromethyl))argentate(III) complexes [nBu4N]+[Ag(Ar)(CF3)3]- and their C(sp2)-CF3 bond-forming reductive elimination are described. Mechanistic studies of the C(sp2)-CF3 reductive elimination from these complexes, including kinetic studies, effect of temperature and solvent, and DFT calculations, indicate that the C(sp2)-CF3 bond-forming process occurred via a concerted reductive elimination pathway.

Fluoroform-derived CuCF3 for low-cost, simple, efficient, and safe trifluoromethylation of aryl boronic acids in air

Easy does it: Aryl boronic acids undergo smooth and selective trifluoromethylation with low-cost fluoroform-derived CuCF3 in DMF in non-dried air. The reaction occurs under mild conditions (1 atm, room temperature), exhibits unprecedented funct