642481-99-0Relevant articles and documents
New Synthesis of Optically Active 5-Isoxazolidinones and β-Amino Acids
Luisi, Renzo,Capriati, Vito,Florio, Saverio,Vista, Teresa
, p. 9861 - 9864 (2007/10/03)
A new simple and stereoselective synthesis of 5-isoxazolidinones based on the reaction of lithiated 2-isopropyl-2-oxazolines with nitrones is described. A chiral version of such a methodology allows the preparation of highly enantioenriched 5-isoxazolidinones which are useful precursors for the synthesis of β-amino acids.