64254-25-7Relevant academic research and scientific papers
Oxidation of amines with hyper valent Tert-butylperoxyiodanes: Synthesis of imines and Tert-butylperoxyamino acetalsh
Ochiai, Masahito,Kajishima, Daisuke,Sueda, Takuya
, p. 71 - 76 (2007/10/03)
Reaction of secondary amines with 1-tert-butylperoxy-1,2-benziodoxol-3(1H)-one (2) undergoes dehydrogenation to afford imines in the presence of K2CO3, while oxidation of tertiary amines without base produces tert-butylperoxyamino acetals.
Amine Peroxides as Potential Antimalarials
Vennerstrom, Jonathan L.
, p. 64 - 67 (2007/10/02)
Six model amine peroxides (4-9) were synthesized as targeted antimalarial oxidants.They were approximately 1 order of magnitude more potent than tert-butyl hydroperoxide (3) in vitro against Plasmodium falciparum, but like 3, they were inactive in vivo against Plasmodium berghei.
