64281-29-4

Usage

Uses

Used in Pharmaceutical Industry:
4-(2-AMINOETHYLAMINO)-PYRIDINE HYDROCHLORIDE is used as a chemical intermediate for the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Dye Production:
AEAP is used as a building block in the production of dyes, playing a crucial role in the creation of colorants for various applications.
Used in Agrochemicals:
4-(2-AMINOETHYLAMINO)-PYRIDINE HYDROCHLORIDE is utilized in the production of agrochemicals, helping to develop substances that protect and enhance crop yields.
Used in Fine Chemicals:
AEAP is used as a building block in the production of other fine chemicals, contributing to the creation of specialty compounds for various industries.
Used in Research and Development:
4-(2-AMINOETHYLAMINO)-PYRIDINE HYDROCHLORIDE is employed in various research and development projects, aiding in the advancement of organic chemistry and the discovery of new applications for this versatile compound.

InChI:InChI=1/C7H11N3.ClH/c8-3-6-10-7-1-4-9-5-2-7;/h1-2,4-5H,3,6,8H2,(H,9,10);1H

Upstream product

• 626-61-9 4-Chloropyridine 
• 107-15-3 ethylenediamine 
• 19524-06-2 4-bromopyridine hydrochloride 
• 7379-35-3 4-chlorpyridine hydrochloride 

Downstream Products

• 362709-34-0 N-[2-(4-Pyridinylamino)ethyl]-3-(3,4,8,9-tetrahydro-6-methoxy-3,3,8,8-tetramethylfuro[2,3-h]isoquinolin-1-yl)benzamide 

Relevant academic research and scientific papers

Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD

Enterovirus 71 (EV71) is a major causative agent of hand, foot, and mouth disease (HFMD), which can spread its infections to the central nervous and other systems with severe consequences. The viral caspid protein VP1 is a well-known target for antiviral efficacy because its occupancy by suitable compounds could stabilize the virus capsid, thus preventing uncoating of virus for RNA release. In this Letter, design, synthesis, and biological evaluation of novel anti-EV71 agents (aminopyridyl 1,2,5-thiadiazolidine 1,1-dioxides) are described. One of the most promising compounds (14) showed excellent antiviral activity against EV71 (EC50 = 4 nM) and exhibited excellent in vivo efficacy in the EV71 infected mouse model.

SUBSTITUTED 2H-[1,2,4]TRIAZOLO[4,3-A]PYRAZINES AS GSK-3 INHIBITORS

The invention relates to compounds of formula (I) prodrugs thereof, and the pahrmaceutically acceptabel salts of the compounds and prodrugs, wherein Ra, Rb, R1 and R2 are as defined herein; pharmaceutical compositions thereof; and uses thereof.

Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines

The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein Ra, Rb, R1, and R2 are as defined herein; pharmaceutical compositions thereof; and uses thereof.

New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 3: 7β-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2- ethoxyiminoacetamido] cephalosporins beari

Among the prepared C-3′ substituted-pyridinium cephalosporins, a series of 7β-[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetamido] cephalosporins bearing 4-[3-(aminoalkyl)-ureido]-1-pyridinium at C-3′ showed highly potent antibacterial activity agai

Tnf-alpha production inhibitors

A purpose of the present invention is to provide TNF-α production inhibitors being useful as therapeutic agents for autoimmune diseases such as rheumatoid arthritis. Novel compounds having the structure represented by the general formula [1] or salts ther

Antihypertensive 1-substituted-4-(2-oxo-1-imidazolidinyl) piperidines

A process known per se for the manufacture of oxygenated N-aryl-diazacyclic compounds of the formula STR1 wherein EACH OF R1 and R2 represents a substituted or unsubstituted aryl group and alk represents a lower alkylene group which