64288-76-2Relevant academic research and scientific papers
Simple One-Pot Synthesis of 2-Acylmethylidene-3-methyl-thiazolines
Pauls, Henry W.,Krantz, Allen
, p. 50 - 51 (2007/10/02)
2-Acylmethylidene-3-methylthiazolines 3 (R=alkyl or aryl) are obtained from their precursor acids in one operation.Carboxylic acids 1 are activated with carbodiimide, and treated, in situ, in the presence of 4-dimethylaminopyridine, with 3-methyl-2-methylidene-4-thiazoline (6) (derived from thiazolium salt 2) to yield 2-acylmethylidene-3-methylthiazolines 3.
