643-78-7Relevant articles and documents
A Molecular Imaging Approach to Mercury Sensing Based on Hyperpolarized 129Xe Molecular Clamp Probe
Guo, Qianni,Zeng, Qingbin,Jiang, Weiping,Zhang, Xiaoxiao,Luo, Qing,Zhang, Xu,Bouchard, Louis-S.,Liu, Maili,Zhou, Xin
supporting information, p. 3967 - 3970 (2016/03/16)
Mercury pollution, in the form of mercury ions (Hg2+), is a major health and environmental hazard. Commonly used sensors are invasive and limited to point measurements. Fluorescence-based sensors do not provide depth resolution needed to image spatial distributions. Herein we report a novel sensor capable of yielding spatial distributions by MRI using hyperpolarized 129Xe. A molecular clamp probe was developed consisting of dipyrrolylquinoxaline (DPQ) derivatives and twocryptophane-A cages. The DPQ derivatives act as cation receptors whereas cryptophane-A acts as a suitable host molecule for xenon. When the DPQ moiety interacts with mercury ions, the molecular clamp closes on the ion. Due to overlap of the electron clouds of the two cryptophane-A cages, the shielding effect on the encapsulated Xe becomes important. This leads to an upfield change of the chemical shift of the encapsulated Xe. This sensor exhibits good selectivity and sensitivity toward the mercury ion. This mercury-activated hyperpolarized 129Xe-based chemosensor is a new concept method for monitoring Hg2+ ion distributions by MRI. In a pinch: A novel sensor is reported that is capable of yielding spatial distributions of mercury ions by MRI, using hyperpolarized 129Xe. This clamp probe (see figure) consists of dipyrrolylquinoxaline (DPQ) derivatives and two cryptophane-A cages. The DPQ derivatives act as cation receptors, whereas cryptophane-A acts as a suitable host molecule for xenon. This sensor exhibits good selectivity and sensitivity toward the mercury ions.
Fluoride-selective optical sensor based on the dipyrrolyl- tetrathiafulvalene chromophore
Rivadehi, Shadi,Reid, Ellen F.,Hogan, Conor F.,Bhosale, Sheshanath V.,Langford, Steven J.
supporting information; experimental part, p. 705 - 709 (2012/02/03)
A chemosensor bearing dipyrrolyl motifs as recognition sites and a tetrathiafulvalene redox tag has been evaluated as an optical and redox sensor for a series of anions (F-, Cl-, Br-, HSO 4-, CH3COO-, and H 2PO4-) in DCM solution. The receptor shows specific optical signaling for fluoride but little electrochemical effect in solution. The solid-state performance of the sensor leads to measurable changes in water. Design implications towards better systems based on these results and other examples are discussed.
A novel class of Cd(ii), Hg(ii) turn-on and Cu(ii), Zn(ii) turn-off Schiff base fluorescent probes
Hu, Yuan,Li, Qian-Qian,Li, Hua,Guo, Qian-Ni,Lu, Yun-Guo,Li, Zao-Ying
scheme or table, p. 11344 - 11352 (2011/02/16)
N,N′-((5,5′-(Quinoxaline-2,3-diyl)bis(1H-pyrrole-5,2-diyl)) bis(methanylylidene))bis(4-methoxyaniline) 4 and N,N′-((5,5′- (quinoxaline-2,3-diyl)-bis(1H-pyrrole-5,2-diyl))bis(methanylylidene))dianiline 5 have been prepared and structurally characterized. The X-ray crystal structures of compounds 4 and 4a have been determined. These compounds displayed good sensitivity toward transition metal ions with Cd(ii), Zn(ii) turn-on and Cu(ii), Hg(ii) turn-off in fluorescence. It is an elegant example of on/off behavior like a lamp. When Cd(ii) or Zn(ii) is added into compounds 4 or 5, the lamp will switch on, and then when Cu(ii) or Hg(ii) is added into the mixture, the lamp will switch off. The binding properties of 4 and 5 for cations were examined by fluorescence spectroscopy. The fluorescence data and crystal structure indicate that a 1:1 stoichiometry complex is formed between compound 4 (or 5) and metal ions, and the binding affinity is very high. The recognition mechanism between compound 4 (or 5) and metal ion was discussed based on the their chemical constructions and the CHEF/CHEQ effect when they interacted with each other.
