643068-23-9Relevant academic research and scientific papers
Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases
Miles, Timothy J.,Barfoot, Christopher,Brooks, Gerald,Brown, Pamela,Chen, Dongzhao,Dabbs, Steven,Davies, David T.,Downie, David L.,Eyrisch, Susanne,Giordano, Ilaria,Gwynn, Michael N.,Hennessy, Alan,Hoover, Jennifer,Huang, Jianzhong,Jones, Graham,Markwell, Roger,Rittenhouse, Stephen,Xiang, Hong,Pearson, Neil
scheme or table, p. 7483 - 7488 (2012/02/04)
As part of our wider efforts to exploit novel mode of action antibacterials, we have discovered a series of cyclohexyl-amide compounds that has good Gram positive and Gram negative potency. The mechanism of action is via inhibition of bacterial topoisomer
ANTIBACTERIAL COMPOUNDS
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Page 58, (2008/06/13)
Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man
NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS
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Page/Page column 32; 123, (2010/02/07)
Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives hereof useful in methods of treatment of bacterial infections in mammals, particularly man.
