64330-83-2

Basic information

• Product Name: 1-(2-hydroxyethyl)pyridin-2(1H)-one
• CAS NO: 64330-83-2
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.1519
• Mol File: 64330-83-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 366.8°C at 760 mmHg
• Flash Point: 175.6°C
• Density: 1.202g/cm³
• Vapor Pressure: 7.22E-07mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 1-(2-hydroxyethyl)pyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyethyl)pyridin-2(1H)-one(64330-83-2)
• EPA Substance Registry System: 1-(2-hydroxyethyl)pyridin-2(1H)-one(64330-83-2)

Safety Data

• Hazardous Substances Data: 64330-83-2(Hazardous Substances Data)

Usage

General Description

1-(2-hydroxyethyl)pyridin-2(1H)-one is a chemical compound that consists of a pyridine ring with a hydroxyethyl group attached at the 1 position. It is used as a chelating agent, meaning it can bind to metal ions and form stable complexes. This property makes it useful in industrial and commercial applications, such as in the production of metalworking fluids, detergents, and water treatment. In addition, it has potential pharmaceutical applications, as it can be used to enhance the dissolution and absorption of certain drugs. Overall, 1-(2-hydroxyethyl)pyridin-2(1H)-one is a versatile chemical with a range of useful properties.

Upstream product

• 343269-67-0 1-(2-hydroxy-ethyl)-1H-pyridin-2-one-imine 
• 34941-69-0 1-(2-hydroxyethyl)pyridinium chloride 
• 142-08-5 2-Pyridone 
• 540-51-2 2-bromoethanol 
• 56446-64-1 2-(pyridine-2-yloxy)ethan-1-ol 
• 504-29-0 2-aminopyridine 
• 75-21-8 oxirane 
• 142-08-5 2-hydroxypyridin 

Downstream Products

• 51323-39-8 1-(2-chloro-ethyl)-1H-pyridin-2-one 

Relevant articles and documents

Synthetic access to new pyridone derivatives through the alkylation reactions of hydroxypyridines with epoxides

General methods for the preparation of a variety of pyridone and oxypyridine derivatives are described. 2-,3-,4-Hydroxy pyridine and 2-pyridinemethanol were alkylated with ethylene-, propylene-, and stryrene-oxide and epichlorohydrin in the presence of di

ADENOSINE RECEPTOR BINDING COMPOUNDS

The present invention relates to pharmaceutical compounds and compositions of Formula (I) and methods of treatment using the compounds and compositions, especially for the treatment and/or prevention of a proliferation disorder, such as cancer. Compounds of Formula (I) as further described herein are shown modulators of the adenosine A2A receptor and exhibit antiproliferative activity. Accordingly, these compounds are useful to treat proliferative disorders such as cancer, and other adenosine receptor-related conditions including an inflammatory disease, renal disease, diabetes, vascular disease, lung disease, or an autoimmune disease.

Intramolecular Photocycloadditions of 1-(ω-Alkenyl)-2-pyridones Possessing an Ester Group on the Olefinic Carbon Chain

Photochemical reactions of three kinds of 1-(ω-alkenyl)-2-pyridones 1-8 were investigated.Photosensitized cyloadditions of 1-(ω-alkenyl)-2-pyridones and 1,3-bis(ω-alkenyl)-2-pyridone 2-6 afforded intramolecular cycloadducts across the 5,6-bonds of the 2-pyridones to give the tricyclic lactams 14-18: the additions were site-, regio-, and stereospecific.The yields of the adducts diminished in proportion to increased side-chain length.The one possessing the shortest alkenyl group, 1, and the 1--2-pyridones 7 and 8, however, gave no products.On the other hand, direct irradiation of 3 afforded a bicyclic lactam 19.The intramolecular cycloaddition mechanism was discussed in terms of the excited state of 2-pyridone, as calculated by MNDO-CI method.