64332-71-4 Usage
Type
Synthetic chlorinated nucleoside analog
Antineoplastic
It has the ability to inhibit the growth of cancer cells.
Immunosuppressive
It reduces the activity of the immune system.
Medical Use
Treatment of certain types of cancer, particularly hairy cell leukemia.
Prodrug
It is a precursor to an active drug and needs to be metabolized in the body.
Phosphorylation
It is phosphorylated intracellularly to its active triphosphate form.
DNA Synthesis and Repair Inhibition
The active form inhibits DNA synthesis and repair.
Cell Death
It leads to the death of rapidly dividing cells, particularly cancer cells.
Lymphocyte Reduction
It has immunosuppressive effects by reducing the number of certain types of lymphocytes.
Administration
Intravenously or subcutaneously
Side Effects
Potential serious side effects, including bone marrow suppression and severe immunosuppression.
Restrictions
Its use is restricted due to potential serious side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 64332-71-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,3,3 and 2 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 64332-71:
(7*6)+(6*4)+(5*3)+(4*3)+(3*2)+(2*7)+(1*1)=114
114 % 10 = 4
So 64332-71-4 is a valid CAS Registry Number.
64332-71-4Relevant academic research and scientific papers
Synthesis and antiviral studies of unsaturated analogues of isomeric dideoxynucleosides
Bera, Sanjib,Mickle, Travis,Nair, Vasu
, p. 2379 - 2395 (2007/10/03)
Novel isomeric dideoxynucleosides with unsaturation in the carbohydrate moiety have been synthesized. For example, isod4A was synthesized through a rearrangement reaction involving a cyclonucleoside. Support for the structures of both purine and pyrimidin