64362-17-0Relevant academic research and scientific papers
Triphenylallenyllead: A facile preparation and its use as a propargylating reagent
Seyferth, Dietmar,Son, David Y.,Shah, Sejal
, p. 2105 - 2108 (1994)
Triphenylallenyllead, which is easily prepared by reaction of the readily available Ph3PbMgBr (in situ, via 3 PhMgBr + PbCl2 in THF) with propargyl bromide, reacts with aldehydes in the presence of a Lewis acid (BF3·OEt2 or TiCl4) to give homopropargylic alcohols, RCH(OH)CH2C≡CH, in good yield. Propargylation of ketones requires transmetalation of PH3PbCH=C=CH2 with PhLi to CH2=C=CHLi and reaction of the latter with the ketone.
