643726-36-7Relevant academic research and scientific papers
Synthesis of Racemic and Enantiomerically Pure (R*,R*,R* )-Tris(α-methylbenzyl)phosphane - X-ray Crystal Structures of the Phosphane Oxides and Borane Complexes
Wyatt, Paul,Eley, Helen,Charmant, Jonathan,Daniel, Berian J.,Kantacha, Anob
, p. 4216 - 4226 (2003)
An asymmetric synthesis of C3-symmetric phosphane 1 has been achieved. Two of the α-methylbenzyl groups were introduced as nucleophiles (using an α-methylbenzyl Grignard reagent), and asymmetry was introduced by resolution using (R)-α-methylbenzylamine. The final α-methylbenzyl group was introduced as an electrophile (α-methylbenzyl iodide) in a modestly selective reaction. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
