64373-81-5Relevant academic research and scientific papers
Efficient synthesis of the anticancer β-elemene and other bioactive elemanes from sustainable germacrone
Barrero, Alejandro F.,Herrador, M. Mar,Quilez Del Moral, Jose F.,Arteaga, Pilar,Meine, Niklas,Perez-Morales, M. Carmen,Catalan, Julieta V.
, p. 1118 - 1125 (2011)
Highly efficient preparations of anticancer β-elemene and other bioactive elemanes were carried out using the natural product germacrone as a renewable starting material. The syntheses were achieved in only 3-5 steps with excellent overall yields (43-54%). An enantioselective approach to these molecules is also described
