643744-76-7Relevant academic research and scientific papers
A new strategy for the synthesis of (±)-Lupinine and (±)-epilupinine via cyclization of α-sulfinyl carbanions
Pohmakotr, Manat,Seubsai, Anusorn,Numeechai, Pornthep,Tuchinda, Patoomratana
, p. 1733 - 1736 (2008/12/22)
(±)-Lupinine and (±)-epilupinine have been prepared starting from commercially available δ-valerolactam. The synthetic route involves the advantages of the cyclization based on α-sulfmyl carbanions.
A general synthetic route to 1-azabicyclo[m.n.0]alkenes via cyclisation based on α-sulfinyl carbanions
Pohmakotr, Manat,Numechai, Pornthep,Prateeptongkum, Saisuree,Tuchinda, Patoomratana,Reutrakul, Vichai
, p. 3495 - 3497 (2007/10/03)
A general synthetic route to 1-azabicyclo[m.n.0]alkenes via cyclisation based on α-sulfinyl carbanions was presented. The intramolecular nucleophillic addition of α-sulfinyl carbanions afforded 1-azabicyclo[m.n.0]alkenes in good yields. It is reported that the developed strategy should provide a general solution for the synthesis of various classes of 1-azabicyclic alkaloids.
