17742-54-0

Basic information

• Product Name: Benzene, [(4-bromobutyl)thio]-
• Synonyms: 4-phenylmercapto-butylbromide;4-bromo-1-phenylsulfanylbutane;4-phenylsulfanyl-1-bromobutane;4-phenylthiobutyl bromide
• CAS NO: 17742-54-0
• Molecular Formula: C10H13BrS
• Molecular Weight: 245.183
• Mol File: 17742-54-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 112-114 °C(Press: 0.6 Torr)
• Density: 1.33±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzene, [(4-bromobutyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(4-bromobutyl)thio]-(17742-54-0)
• EPA Substance Registry System: Benzene, [(4-bromobutyl)thio]-(17742-54-0)

Safety Data

• Hazardous Substances Data: 17742-54-0(Hazardous Substances Data)

Upstream product

• 5162-44-7 1-bromo-4-butene 
• 108-98-5 thiophenol 
• 110-52-1 1,4-dibromo-butane 
• 930-69-8 sodium thiophenolate 
• 110-01-0 thiophene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Downstream Products

• 62358-98-9 7-Phenylthio-3-heptanon 
• 643744-68-7 1-(4-phenylsulfanylbutyl)pyrrolidin-2-one 
• 1453066-45-9 9-O-(4-thiophenyl)butyl-berberine bromide 
• 1353585-72-4 1-(1H-imidazol-1-yl)-4-(phenylsulfanyl)butane hydrochloride 
• 1290046-85-3 C₂₀H₂₅NO₃S 
• 1284281-89-5 3-benzenesulfinyl-1-benzyloxypiperidin-2-one 
• 1284281-76-0 (4-benzenesulfinylbutyl)-N-benzyloxycarbamic acid ethyl ester 
• 89432-50-8 6-(4-phenylmercapto-butoxy)-4,4-dimethyl-4H-3,1-benzoxazin-2-one 
• 72180-47-3 6-(4-phenylsulfonyl-butoxy)-3,4-dihydro-carbostyril 
• 5755-78-2 (4-bromobutane-1-sulfonyl)-benzene 
• 124099-07-6 1-(2'-Methoxy-4'-methylphenyl)-8-(phenylthio)octan-4-one 
• 136044-01-4 (R)-4-Benzyl-3-[(1S,2R)-4-ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarbonyl]-oxazolidin-2-one 
• 136044-02-5 (1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester 
• 136044-04-7 (1R,4S,5R)-5-(3-Benzenesulfinyl-propyl)-1-ethyl-2-oxa-bicyclo[2.2.2]octan-3-one 

Relevant articles and documents

Sulfone derivatives as 5-HT7 receptor ligands

The present invention relates to sulfone derivatives of formula (I): Ar—SO2—CR2R3-L-N(R1)2??I wherein Ar, L, R1, R2 and R3 are as defined herein, and pharmaceutically

BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF

A benzoic acid compound of the formula wherein each symbol is as defined in the specification, an optical isomer thereof and a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprising this compound and a pharmaceutically acceptable additive, a serotonin 4 receptor agonist comprising this compound as an active ingredient, a gastrointestinal prokinetic agent and a therapeutic agent for gastrointestinal diseases. The compound of the present invention shows selective and high affinity for serotonin 4 receptors, activates same, is useful as a pharmaceutical agent for the prophylaxis and treatment of gastrointestinal diseases (e.g., reflux esophagitis; gastroesophageal reflux such as that accompanying cystic fibrosis; Barrett syndrome; intestinal pseudoileus; acute or chronic gastritis; gastric or duodenal ulcer; Crohn's disease; non-ulcer dyspepsia; ulcerative colitis; postgastrectomy syndrome; postoperative digestive function failure; delayed gastric emptying caused by gastric neurosis, gastroptosis, diabetes, and the like; gastrointestinal disorders such as indigestion, meteorism, abdominal indefinite complaint, and the like; constipation such as atonic constipation, chronic constipation, and that caused by spinal cord injury, pelvic diaphragm failure and the like; and irritable bowel syndrome), central nervous disorders (e.g., schizophrenia, depression, anxiety, disturbance of memory and dementia), cardiac function disorders (e.g., cardiac failure and myocardial ischemia), urinary diseases (e.g., dysuria caused by urinary obstruction, ureterolith, prostatomegaly, spinal cord injury, pelvic diaphragm failure, etc.), and shows superior absorption.