64376-00-7Relevant academic research and scientific papers
Selective exploitation of acetoacetate carbonyl groups using imidazolium based ionic liquids: synthesis of 3-oxo-amides and substituted benzimidazoles
Chakraborty, Ankita,Majumdar, Swapan,Maiti, Dilip K.
, p. 3298 - 3302 (2016/07/11)
An unprecedented Br?nsted base ionic liquid tuned selective aminolysis of ester carbonyl of acetoacetates is demonstrated to achieve acetoacetamide derivatives. Other imidazolium ionic liquid performs an efficient cyclization catalysis involving acetoacetate-carbonyl groups and o-phenylenediamine at elevated temperature to produce benzimidazoles via C–C bond cleavage of intermediate 1,5-benzodiazepinones under solvent-free conditions.
An Easy Route to Synthesize 1,5-Arylodiazepin-2-ones
Bougrin, Khalid,Bennani, A. Kella,Tetouani, Souad Fkih,Soufiaoui, Mohamed
, p. 8373 - 8376 (2007/10/02)
A series of 1,5-arylodiazepin-2-ones is prepared by the condensation of the approptiate o-β-arylenediamines with β-ketoesters in xylene under microwave irradiation.The reaction time is shortened to 10 mn, and the products are obtained in high yields.No by products are observed.Specific effects of microwaves are evidenced as no reaction occurs by classical heating in same conditions. - Key Words: Condensation; Microwave; 1,5-Arylodiazepin-2-ones.
AN EFFICIENT PREPARATION OF 4-ARYLMETHYLISOXAZOL-5-ONES BY SELECTIVE REDUCTION OF THE 4-ARYLMETHYLENEISOXAZOL-5-ONES
Risitano, Francesco,Grassi, Giovanni,Foti, Francesco
, p. 5893 - 5896 (2007/10/02)
An efficient selective reduction of the exocyclic double bond of the 4-arylmethyleneisoxazol-5-ones with o-phenylenediamines and aldehydes is described. 4-arylmethylisoxazol-5-ones are produced in high yields together with comparable quantities of benzimidazoles.
