64376-40-5Relevant academic research and scientific papers
Preparation of 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2: H -pyrrol-2-ones via base-assisted cyclization of 3-cyanoketones
Aksenov, Nicolai A.,Aksenov, Dmitrii A.,Kurenkov, Igor A.,Aksenov, Alexander V.,Skomorokhov, Anton A.,Prityko, Lidiya A.,Rubin, Michael
, p. 16236 - 16245 (2021)
A convenient preparative method is developed allowing for expeditious assembly of 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones from routinely available inexpensive synthetic precursors. These compounds could not be prepared via the previously known protocols, as 2-aminofuran derivatives were produced instead.
