343609-17-6 Usage
General Description
(E)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-phenylprop-2-en-1-one, also known as Safrole, is a chemical compound with a complex structure that contains a benzodioxole ring and a phenylprop-2-en-1-one moiety. It is commonly found in essential oils derived from sassafras and camphor trees and is used as a precursor in the synthesis of various substances, including drugs and fragrances. Safrole has been studied for its potential pharmacological properties, including antibacterial, antifungal, and anticancer activities. However, it is also known to be toxic and carcinogenic, leading to its regulation and restriction in many countries. Despite its potential medicinal uses, the health risks associated with its consumption have led to limited research and development in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 343609-17-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,3,6,0 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 343609-17:
(8*3)+(7*4)+(6*3)+(5*6)+(4*0)+(3*9)+(2*1)+(1*7)=136
136 % 10 = 6
So 343609-17-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H14O3/c18-15(8-6-13-4-2-1-3-5-13)14-7-9-16-17(12-14)20-11-10-19-16/h1-9,12H,10-11H2/b8-6+
343609-17-6Relevant articles and documents
Design, biological evaluation and 3D QSAR studies of novel dioxin-containing triaryl pyrazoline derivatives as potential B-Raf inhibitors
Yang, Yu-Shun,Yang, Bing,Zou, Yan,Li, Guigen,Zhu, Hai-Liang
, p. 3052 - 3061 (2016)
A series of novel dioxin-containing triaryl pyrazoline derivatives C1-C20 have been synthesized. Their B-Raf inhibitory and anti-proliferation activities were evaluated. Compound C6 displayed the most potent biological activity against B-RafV600E/su
Development of a general palladium-catalyzed carbonylative heck reaction of aryl halides
Wu, Xiao-Feng,Neumann, Helfried,Spannenberg, Anke,Schulz, Thomas,Jiao, Haijun,Beller, Matthias
supporting information; experimental part, p. 14596 - 14602 (2010/12/24)
The first general palladium-catalyzed carbonylative vinylation of aryl halides with olefins in the presence of CO has been developed. Applying a catalyst system consisting of [(cinnamyl)PdCl]2 and bulky imidazolyl-phosphine ligand L1 allows for the efficient and selective synthesis of α,β-unsaturated ketones under mild reaction conditions. Starting from easily available aryl halides and olefins, versatile building blocks can be prepared in a straightforward manner. The generality and functional group tolerance of this novel protocol is demonstrated.
