64382-92-9

Basic information

• Product Name: 2,4-DIBROMO-1-(BROMOMETHYL)BENZENE
• Synonyms: 2,4-DIBROMO-1-(BROMOMETHYL)BENZENE
• CAS NO: 64382-92-9
• Molecular Formula: C₇H₅Br₃
• Molecular Weight: 329
• EINECS: -0
• Mol File: 64382-92-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-DIBROMO-1-(BROMOMETHYL)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIBROMO-1-(BROMOMETHYL)BENZENE(64382-92-9)
• EPA Substance Registry System: 2,4-DIBROMO-1-(BROMOMETHYL)BENZENE(64382-92-9)

Safety Data

• Hazardous Substances Data: 64382-92-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,4-DIBROMO-1-(BROMOMETHYL)BENZENE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to facilitate the creation of complex organic molecules that possess therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-DIBROMO-1-(BROMOMETHYL)BENZENE is utilized as a precursor in the production of insecticides and fungicides, contributing to the development of compounds that protect crops from pests and diseases.
Given the compound's classification as a potential hazard, it is imperative that its applications are carefully managed and controlled to ensure the safety of both the environment and human health.

Upstream product

• 31543-75-6 2,4-dibromotoluene 
• 611-00-7 2,4-dibromobenzoic acid 
• 666747-06-4 (2,4-dibromophenyl)methanol 

Downstream Products

• 66246-16-0 2-(2,4-dibromophenyl)acetonitrile 
• 666747-06-4 (2,4-dibromophenyl)methanol 
• 611-00-7 2,4-dibromobenzoic acid 
• 1346964-77-9 (Z)-1-(2,4-dibromophenyl)pent-3-en-2-one 
• 1346964-94-0 (E)-1-(2,4-dibromophenyl)pent-3-en-2-one 
• 92104-02-4 6-bromo-2-phenylbenzofuran 
• 1285505-91-0 C₁₀H₈Br₂O₂ 
• 1285505-89-6 C₁₂H₁₂Br₂O₂ 
• 5629-98-1 2,4-dibromobenzaldehyde 
• 1285505-86-3 N-[(E)-3-(2,4-dibromo-phenyl)-2-methyl-acryloyl]-guanidine 

Relevant articles and documents

Optimization of the chromone scaffold through QSAR and docking studies: Identification of potent inhibitors of ABCG2

The membrane transporter BCRP/ABCG2 has emerged as a privileged biological target for the development of small compounds capable of abolishing multidrug resistance. In this context, the chromone skeleton was found as an excellent scaffold for the design o

Synthetic method 2 and 4 - dibromobenzyl alcohol

The invention provides 2-4 - dibromobenzyl alcohol synthesis method, and the specific steps are as follows: S1, 2, 4 - dibromotoluene is brominated 2 and 4 - dibromobenzyl bromide in a radical initiator. S2 represents 2, 4 - dibromobenzylacetate in acetat

COMPOUNDS AND USES THEREOF

The present disclosure features compounds useful for the treatment of BAF complex-related disorders.

tBuOK-Promoted Cyclization of Imines with Aryl Halides

A transition-metal-free indole synthesis using radical coupling of 2-halotoluenes and imines via the later-stage C-N bond construction was reported for the first time. It includes an aminyl radical generation by C-H cleaving addition of 2-halotoluenes to imines via the carbanion radical relay and an intramolecular coupling of aryl halides with aminyl radicals. One standard condition can be used for all halides including F, Cl, Br, and I. No extra oxidant or transition metal is required.

Strategy for Overcoming Full Reversibility of Intermolecular Radical Addition to Aldehydes: Tandem C-H and C-O Bonds Cleaving Cyclization of (Phenoxymethyl)arenes with Carbonyls to Benzofurans

An intermolecular addition of carbon radicals enabled by a cascade radical coupling strategy is developed. It includes an intermolecular alkyl radical addition to a carbonyl group followed by an intramolecular alkoxy radical addition to haloarenes and produces substituted benzofurans in high yields. The radical nature of this reaction is explored by radical trapping experiments and EPR analysis. The mechanism is investigated by KIE experiments and control experiments. This method could provide rapid and practical access to the key intermediate of TAM-16, a safe and potent antibacterial agent for treating tuberculosis, and, therefore, is of great importance for organic synthesis and the pharmaceutical industry.

NOVEL ACYL GUANIDINE DERIVATIVES

The present invention provides a pharmaceutical which possesses an excellent inhibitory effect on NHE3 (Na+/H+ exchanger type 3) and effectively improves diseases or conditions of organs in which NHE3 is expressed.

The first syntheses of 3-bromofascaplysin, 10-bromofascaplysin and 3,10-dibromofascaplysin-marine alkaloids from Fascaplysinopsis reticulata and Didemnum sp. by application of a simple and effective approach to the pyrido[1,2-a:3,4-b′]diindole system

A simple and practical approach for the synthesis of the marine sponge pigment fascaplysin was used for the total syntheses of its natural derivatives, the marine alkaloids 3-bromofascaplysin, 10-bromofascaplysin, and 3,10-dibromofascaplysin. The conditions of each step were revised, and as a result these compounds were produced by identical procedures with total yields of 40-43%.