666747-06-4

Basic information

• Product Name: 2,4-Dibromobenzyl Alcohol
• Synonyms: 2,4-Dibromobenzyl alcohol;2,4-dibromoBenzenemethanol
• CAS NO: 666747-06-4
• Molecular Formula: C₇H₆Br₂O
• Molecular Weight: 265.93
• Product Categories: Alcohols;Bromine Compounds
• Mol File: 666747-06-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 80.0 to 84.0 °C
• Boiling Point: 322.1ºC at 760 mmHg
• Flash Point: 148.6ºC
• Appearance: /Solid
• Density: 1.960
• Vapor Pressure: 0.000117mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.74±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 2,4-Dibromobenzyl Alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dibromobenzyl Alcohol(666747-06-4)
• EPA Substance Registry System: 2,4-Dibromobenzyl Alcohol(666747-06-4)

Safety Data

• Hazardous Substances Data: 666747-06-4(Hazardous Substances Data)

Usage

Uses

It is an halogenated compound for proteomics research. Also used as a intermediate for pharmaceutical.

InChI:InChI=1/C7H6Br2O/c8-6-2-1-5(4-10)7(9)3-6/h1-3,10H,4H2

Upstream product

• 64382-92-9 2,4-dibromo-1-(bromomethyl)benzene 
• 31543-75-6 2,4-dibromotoluene 
• 54335-33-0 methyl 2,4-dibromobenzoate 
• 611-00-7 2,4-dibromobenzoic acid 
• 78222-69-2 2,4-dibromobenzonitrile 
• 615-57-6 2,4-dibromo-aniline 
• 5629-98-1 2,4-dibromobenzaldehyde 
• 858841-41-5 2,4-dibromo-benzyl chloride 

Downstream Products

• 611-00-7 2,4-dibromobenzoic acid 
• 858841-41-5 2,4-dibromo-benzyl chloride 
• 98434-44-7 (2,4-dibromophenyl)acetic acid 
• 943906-71-6 2,4-dibromophenethyl alcohol 
• 66246-16-0 2-(2,4-dibromophenyl)acetonitrile 
• 1201913-61-2 2,4-dibromo-1-(1-methoxy-1-methylethoxymethyl)benzene 
• 249897-21-0 2-bromo-1-(1-methoxy-1-methylethoxymethyl)benzene 
• 1201913-76-9 4-bromo-1-(1-methoxy-1-methylethoxymethyl)benzene 
• 903565-83-3 (1S,3′R,4′S,5′S,6′R)-6-[(4-ethylphenyl)methyl]-3′,4′,5′,6′-tetrahydro-6′-(hydroxymethyl)-spiro[isobenzofuran-1(3H),2′-[2H]pyran]-3′,4′,5′-triol 
• 1201913-63-4 2,3,4,5-tetrakis(trimethylsiloxy)-6-trimethylsilyloxymethyl-2-(5-(4-ethylphenyl)hydroxymethyl-2-(1-methoxy-1-methylethoxymethyl)phenyl)tetrahydropyran 
• 1201913-64-5 2,3,4,5-tetrakis(trimethylsilyloxy)-6-trimethylsilyloxymethyl-2-(5-bromo-2-(1-methoxy-1-methylethoxymethyl)phenyl)tetrahydropyran 
• 1201913-74-7 (1S,3'R,4'S,5'R,6'R)-6-(4-ethylbenzyl)-6′-((pivaloyloxy)-methyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triyl tris(2,2-dimethylpropanoate) 
• 90110-98-8 3-bromo-4-(hydroxymethyl)benzonitrile 
• 64382-92-9 2,4-dibromo-1-(bromomethyl)benzene 

Relevant articles and documents

Synthetic method 2 and 4 - dibromobenzyl alcohol

The invention provides 2-4 - dibromobenzyl alcohol synthesis method, and the specific steps are as follows: S1, 2, 4 - dibromotoluene is brominated 2 and 4 - dibromobenzyl bromide in a radical initiator. S2 represents 2, 4 - dibromobenzylacetate in acetat

IMMUNE ADJUSTMENT COMPOUND, USE THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention provides a compound represented by formula I, wherein R is a halogen element or a C1-C6 alkyl group. The compound has S1 P1 receptor agonist activity and selective specificity and has obviously-shortened half-life in-vivo, and therefore the compound is a high-quality second-generation S1P1 receptor agonist. The present invention also provides a use of the compound in preparing medicine for treating diseases or symptoms mediated by an S1P1 receptor, a pharmaceutical composition comprising the compound, and uses of the compound and the pharmaceutical composition in treating diseases or symptoms mediated by the S1 P1 receptor.