64400-76-6Relevant articles and documents
BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS
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Page/Page column 67, (2019/06/23)
Aspects of the present disclosure include conformationally restricted analogs of catecholamine type compounds (e.g., isoprenaline, adrenaline, noradrenaline) which activate β2AR with high selectivity over β1AR. The subject beta-2 selective adrenergic rece
Facile synthesis of octahydrobenzo[h]isoquinolines: Novel and highly potent D1 dopamine agonists
Bonner, Lisa A.,Chemel, Benjamin R.,Watts, Val J.,Nichols, David E.
experimental part, p. 6763 - 6770 (2010/10/20)
The octahydrobenzo[h]isoquinoline scaffold is of interest as a conformationally-restricted phenethylamine that may be useful for constructing biologically active products. Surprisingly, however, no tractable synthesis of this ring system has been reported
Synthesis and evaluation of the bioactivity of simplified analogs of the seco-pseudopterosins; progress toward determining a pharmacophore
Tanis, Virginia M.,Moya, Claudia,Jacobs,Little, R. Daniel
, p. 10649 - 10663 (2008/12/23)
The pseudopterosins are marine natural products that display significant anti-inflammatory and wound healing properties. We describe the synthesis of six structural analogs of the seco-pseudopterosin-like core that are devoid of all but one of the stereoc