3893-01-4

Usage

Uses

Used in Organic Synthesis:
2,3-Dimethoxybenzyl Chloride is used as a reagent or intermediate for various chemical reactions in the field of organic synthesis. Its reactive properties allow it to participate in a series of significant chemical transformations under controlled conditions.
Used in Pharmaceutical Industry:
2,3-Dimethoxybenzyl Chloride is used as a key intermediate in the synthesis of certain pharmaceutical compounds. Its unique structure and reactivity enable the creation of new drug molecules with potential therapeutic applications.
Used in Chemical Research:
2,3-Dimethoxybenzyl Chloride is employed as a research tool in academic and industrial laboratories. Its reactivity and chemical properties make it a valuable compound for studying reaction mechanisms and exploring new synthetic pathways.

InChI:InChI=1/C9H11ClO2/c1-11-8-5-3-4-7(6-10)9(8)12-2/h3-5H,6H2,1-2H3

Upstream product

• 5653-67-8 2,3-dimethoxybenzyl alcohol 
• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 108-48-5 2,6-dimethylpyridine 

Downstream Products

• 90704-69-1 N,N-dimethyl-2,3-dimethoxybenzylamine 
• 875240-19-0 1,2-bis-chloromethyl-3,4-dimethoxy-benzene 
• 630-02-4 octacosane 
• 7461-75-8 1,2-dimethoxy-3-pentadecyl-benzene 
• 40101-08-4 1,2-bis(2,3-dimethoxyphenyl)ethane 
• 4468-57-9 2-(2,3-dimethoxyphenyl)acetonitrile 
• 53663-28-8 N-methyl-N-[(2,3-dimethoxyphenyl)methyl]amine 
• 87664-47-9 2-(2,3-Dimethoxybenzyl)-pyrrol 
• 87664-48-0 3-(2,3-Dimethoxybenzyl)-pyrrol 
• 75875-48-8 3,4-dihydro-6,7-dimethoxy-N-(2,3-dimethoxybenzyl)isoquinolinium chloride 
• 122670-45-5 N-(2,3-Dimethoxybenzyl)diethoxyacetamide 
• 126036-02-0 4-(2,3-dimethoxyphenyl)-3-methyl-1-butene 
• 126036-03-1 1,2-Dimethoxy-3-((E)-pent-3-enyl)-benzene 
• 220293-99-2 ethyl 4-(2,3-dimethoxyphenyl)butanoate 

Relevant academic research and scientific papers

PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES

[Problem] A problem is presented in that conventional photochromic compounds cannot be considered adequate in terms of the colorizing/decolorizing rate and durability, and the production process therefore has many steps. The present invention provides an industrially applicable photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability and can also be synthesized at a low cost. [Solution] This compound is characterized in that etheric oxygen atoms are bonded to the carbon atoms at position 1 of a pyranoquinazoline (8H-pyrano[3,2-f]quinazoline) skeleton and position 10 of a naphthopyran (3H-naphtho[2,1-b]pyran) skeleton, said compound having photochromic properties and being a photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability. Also provided is an industrially applicable photochromic compound that can be synthesized at a low cost.

NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY

The present invention generally concerns particular methods and compositions for antimicrobial therapy. In particuarl embodiments, the compositions target DXR. In specific embodiments, the compositions are electron-deficient heterocyclic rings.

5- substituted tetralones as inhibitors of ras farnesyl trransferase

The present invention provides novel 5-substituted tetralones of Formulas (I), (II), (III) and (IV) and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, which are useful for treating and preventing uncontrolled or abnormal proliferation of tissues, such as cancer, atherosclerosis, restenosis, and psoriasis. Specifically, the present invention relates to compounds that inhibit the farnesyl transferase enzyme.

An improved and versatile method for the rapid synthesis of aryldihydrobenzofuran systems by a boron tribromide-mediated cyclization reaction

Boron tribromide is presented as a highly reactive reagent that simultaneously allows the demethylation and fully diastereoselective cyclization of different precursor molecules, obtained by an aldol-type reaction, to a series of hydroxylated aryldihydrobenzofuran systems in racemic form. The latter are often found as key structures in natural compounds of different classes. Syntheses of educts, which mainly took advantage of a versatile Rieche formylation, are also described.

Therapeutic agent for liver disease and piperazine derivatives

A therapeutic agent for liver disease containing as an active ingredient a piperazine derivative having the formula: STR1 wherein, A represents a phenyl, p-benzoquinonyl or cumarinyl group which may have at least one substituent selected from the group consisting of halogen, alkyl, fluoroalkyl, formyl, alkoxycarbonyl, acyl, hydroxy, alkoxy, acyloxy, glycosyloxy, amino, alkylamino, mercapto, alkylthio and nitro; B represents a single bond or a straight chain alkylene group containing 1-4 carbon atoms which may have at least one substituent selected from the group consisting of alkyl, aryl, aralkyl, hydroxy and oxo; R represents an atom or a group selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, alkyl, cycloalkyl, aralkyl and aryl; and n is 2 or 3, or its pharmaceutically acceptable salt is disclosed.

Process for preparing fluorinated amino-nitriles

Certain α-(fluoromethyl or difluoromethyl)-α-aminoacetonitriles are prepared by treating the appropriate α-(fluoromethyl or difluoromethyl) ketimine magnesium halide with hydrogen cyanide or with an alkali metal cyanide or ammonium cyanide and a proton source. The products are useful as intermediates for making α-(fluoromethyl or difluoromethyl)-α-amino acids having pharmacological activity.

Method of depleting endogenous monoamines

2-Amino-2-fluoromethyl-3-(substituted)phenyl propionic acids and derivatives thereof are coadministered with dopamine for the treatment of schizophrenia, mania, tardive dyskinesia, anxiety, or depression.