64403-55-0

Upstream product

• 52469-60-0 2-phenyl-naphtho[1,2-d]oxazole-5-sulfonic acid 
• 98-88-4 benzoyl chloride 
• 116-63-2 1-amino-2-naphthol-4-sulfonic acid 

Downstream Products

• 75511-04-5 2-phenyl-naphtho[1,2-d]oxazole-5-sulfonic acid 4-phenyl-thiazol-2-ylamide 
• 64403-51-6 N-(2-phenyl-naphtho[1,2-d]oxazole-5-sulfonyl)-L-tyrosine 
• 64403-52-7 N-(2-phenyl-naphtho[1,2-d]oxazole-5-sulfonyl)-tryptophan 
• 150940-70-8 N,N-diethyl-2-phenylnaphth<1,2-d>oxazole-5-sulfonamide 
• 75510-94-0 2-phenyl-naphtho[1,2-d]oxazole-5-sulfinic acid 

Relevant academic research and scientific papers

Naphthoxazole Intermediates in the Preparation of 3-Hydroxy-4-(1-alkyl-3-methyl-5-hydroxy-4-pyrazolyl>-azo-1-naphthalenesulfonamide Dyes

Acylation of 4-amino-3-hydroxy-1-naphthalenesulfonic acid (3) with benzoyl chloride in pyridine gave pyridinium 3-hydroxy-4-(N-benzoylamino)-1-naphthalenesulfonate (12) which was converted by thionyl chloride followed by diethylamine into N,N-diethyl-2-phenylnaphthoxazole-5-sulfonamide (14).The naphthoxazole moiety was hydrolyzed with potassium hydroxide and the resulting N,N-diethyl-4-amino-3-hydroxy-1-naphthalenesulfonamide (11) coupled with 1-alkyl-3-methyl-5-pyrazolones.The 2-phenylnaphthoxazole intermediates and various by-products were investigated.