64415-17-4Relevant articles and documents
Synthesis of a new β-naphthothiazole monomethine cyanine dye for the detection of DNA in aqueous solution
El-Shishtawy, Reda M.,Asiri, Abdullah M.,Basaif, Salem A.,Rashad Sobahi
experimental part, p. 1605 - 1609 (2010/06/20)
Novel monomethine cyanine dye (MC) derived from β-naphthothiazole and benzothiazole has been prepared and characterized by 1H and 13C NMR, FTIR, ESIMS, elemental analyses, absorption and fluorescence spectroscopy. The dye was conveniently synthesized by the condensation of two sulfate heterocyclic quaternary salts. The interaction between calf thymus DNA (ct-DNA) in tris(hydroxymethyl)aminomethane-HCl (Tris-HCl) aqueous buffer solution and MC has been studied with spectral fluorescence method. The binding constant value has been determined by fluorescence titration of MC with ct-DNA concentrations. The result obtained is consistent with an intercalative binding interaction between MC and ct-DNA. Compared with ethidium bromide (EB), MC showed a huge fluorescence enhancement upon mixing with ct-DNA.
EXCHANGE OF HALIDE IONS IN ONIUM SALTS. II. REACTION OF 2,3-DIMETHYLBENZOTHIAZOLIUM IODIDE AND 2-METHYLNAPHTHOTHIAZOLIUM SALTS WITH METHYL OR ETHYL SULFATES
Vompe, A. F.,Meshki, L. M.
, p. 1551 - 1554 (2007/10/02)
The first stage in the reaction of 2,3-dimethylbenzothiazolium iodide, 2-methylnaphthothiazolium salts, and tetraethylammonium iodide with methyl or ethyl sulfates is change of the iodide ion for an alkyl sulfate residue; increase in temperature leads to the dissociation of the methyl sulfate anion and its conversion into the bisulfate ion.A carbene is formed intermediately.