64419-14-3

Basic information

• Product Name: 2-Thiophenecarboxamide,N-(4-methoxyphenyl)-
• Synonyms: 2-Thiophenecarboxamide,N-(4-methoxyphenyl)-;N-(4-METHOXYPHENYL)-2-THIOPHENECARBOXAMIDE
• CAS NO: 64419-14-3
• Molecular Formula: C₁₂H₁₁NO₂S
• Molecular Weight: 233.28624
• Mol File: 64419-14-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 137-140 °C
• Boiling Point: 293.8±20.0 °C(Predicted)
• Appearance: /
• Density: 1.283±0.06 g/cm3(Predicted)
• PKA: 12.06±0.70(Predicted)
• CAS DataBase Reference: 2-Thiophenecarboxamide,N-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiophenecarboxamide,N-(4-methoxyphenyl)-(64419-14-3)
• EPA Substance Registry System: 2-Thiophenecarboxamide,N-(4-methoxyphenyl)-(64419-14-3)

Safety Data

• Hazardous Substances Data: 64419-14-3(Hazardous Substances Data)

Upstream product

• 5271-67-0 2-Thiophenecarbonyl chloride 
• 496-15-1 1-indoline 
• 100-17-4 para-methoxynitrobenzene 
• 328026-80-8 indolin-1-yl(thiophen-2-yl)methanone 
• 5813-89-8 2-thiophenylcarboxamide 
• 696-62-8 para-iodoanisole 
• 527-72-0 2-thiophenylcarboxylic acid 
• 3437-95-4 2-Iodothiophene 
• 104-94-9 4-methoxy-aniline 
• 13939-06-5 molybdenum hexacarbonyl 
• 1003-09-4 2-bromothiophene 
• 1038403-99-4 N-acetoxy-2-thiophenecarboxamide 
• 70744-47-7 (p-methoxyphenyl)tri-n-butylstannane 

Downstream Products

• 1137746-62-3 N-(p-anisyl)thiophene-2-carboxyimidoyl chloride 

Relevant articles and documents

Manganese-Mediated Reductive Transamidation of Tertiary Amides with Nitroarenes

Amides are an important class of organic compounds, which have widespread industrial applications. Transamidation of amides is a convenient method to generate new amides from existing ones. Tertiary amides, however, are challenging substrates for transamidation. Here we describe an unconventional approach to the transamidation of tertiary amides using nitroarenes as the nitrogen source under reductive conditions. Manganese metal alone mediates the reactions and no additional catalyst is required. The method exhibits broad scope and high functional group tolerance.

Palladium-catalysed multicomponent aminocarbonylation of aryl or heteroaryl halides with Mo(CO)6i and aryl- or heteroarylamines using conventional heating

Di(hetero)arylamides have been synthesized in short reaction times by palladium-catalysed multicomponent aminocarbonylation of either electron-deficient or electron-rich heteroaryl halides and p-iodoanisole with, several, arylamines bearing either electro

Determination of aromaticity indices of thiophene and furan by nuclear magnetic resonance spectroscopic analysis of their anilides

A series of m- and p-substituted anilides of benzoic acid, 2-thienoic acid, and 2-furoic acid were prepared and their 1H and 13C nmr spectroscopic characteristics were examined. In general, good correlations were observed between the chemical shifts of proton and carbon signals of the acyl aromatic rings and the Hammett σ. Plots of the chemical shift values of the carbonyl carbons of the benzanilides against those of the 2-thienamides and 2-furamides gave an excellent correlation and the values of the slopes are 0.79 and 0.52, respectively, in dimethyl sulfoxide-d6. The slopes could be considered as a set of aromaticity index.