64432-04-8

Basic information

• Product Name: 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol
• Synonyms: 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol;Grifolin monomethyl ether
• CAS NO: 64432-04-8
• Molecular Formula: C₂₃H₃₄O₂
• Molecular Weight: 342.51
• Mol File: 64432-04-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol(64432-04-8)
• EPA Substance Registry System: 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol(64432-04-8)

Safety Data

• Hazardous Substances Data: 64432-04-8(Hazardous Substances Data)

Upstream product

• 83897-47-6 3-Methylcyclobutenon 
• 89711-19-3 (4E,8E)-1-Methoxy-5,9,13-trimethyl-tetradeca-4,8,12-trien-1-yne 
• 4179-19-5 1,3-dimethoxy-5-methylbenzene 
• 24163-93-7 farnesyl bromide 
• 64432-03-7 1,3-dimethoxy-5-methyl-2-<(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl>benzene 

Relevant articles and documents

A general approach for the synthesis of phenolic natural products. Facile syntheses of grifolin and colletochlorins B and D

A general approach is established for the synthesis of phenolic compounds having terpenoid side chains: (1) protection of the phenolic hydroxyls in the aromatic precursor by ether formation, (2) coupling the aromatic part with a terpenoid bromide, and (3) deprotection to regenerate the hydroxyl groups. This strategy was successfully applied to the synthesis of colletochlorins B and D and grifolin. Some of the colletochlorin derivatives were found to inhibit the cell growth of P388.