64437-80-5

Basic information

• Product Name: Benzaldehyde, 2-methoxy-5-nitro-, oxime
• CAS NO: 64437-80-5
• Molecular Formula: C8H8N2O4
• Molecular Weight: 196.163
• Mol File: 64437-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-methoxy-5-nitro-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-methoxy-5-nitro-, oxime(64437-80-5)
• EPA Substance Registry System: Benzaldehyde, 2-methoxy-5-nitro-, oxime(64437-80-5)

Safety Data

• Hazardous Substances Data: 64437-80-5(Hazardous Substances Data)

Upstream product

• 25016-02-8 2-methoxy-5-nitrobenzaldehyde 

Downstream Products

• 26177-22-0 2-Dinitromethyl-1-methoxy-4-nitro-benzene 

Relevant articles and documents

HCl-mediated cascade cyclocondensation of oxygenated arylacetic acids with arylaldehydes: one-pot synthesis of 1-arylisoquinolines

In this paper, a concise, open-vessel synthesis of 1-arylisoquinolines is describedviaHCl-mediated intermolecular cyclocondensation of oxygenated arylacetic acids with arylaldehydes in the presence of NH2OH and alcoholic solvents under mild and one-pot reaction conditions. A plausible mechanism is proposed and discussed herein. In the overall reaction process, only water was generated as the byproduct. Various environmentally friendly reaction conditions are investigated for convenient transformationviathe (4C + 1C + 1N) annulation. This protocol provides a highly effective ring closureviathe formations of one carbon-carbon (C-C) bond, two carbon-nitrogen (C-N) bonds and one carbon-oxygen (C-O) bond.