64456-11-7

Upstream product

• 100-39-0 benzyl bromide 
• 33174-54-8 5-formamido-N'-methoxy-1-methyl-1H-imidazole-4-carboxamidine 
• 70276-45-8 5-(Formylbenzylamino)-N'-methoxy-1-methyl-1H-imidazole-4-carboxamidine 
• 70276-54-9 5-(N-Benzylformamido)-1-methyl-1H-imidazole-4-carboxamidine Hydrochloride 

Downstream Products

• 187023-92-3 5-Benzylamino-1-methyl-1H-imidazole-4-carbonitrile 
• 69265-18-5 5-(benzyl-cyano-amino)-1-methyl-1H-imidazole-4-carboxylic acid amide 

Relevant academic research and scientific papers

Bamberger fission and reclosure of 1-alkyl-5-(alkylamino)imidazole-4- carbonitriles leading to their 2-oxo derivatives

1-Methyl-5-(methylamino)imidazole-4-carbonitrile (4a) afforded three minor ring-opened products (5a, 6a, 10a) besides its 2-oxo derivative 3a on treatment with ethyl chloroformate in aqueous sodium bicarbonate. The geometrical isomers of these trisubstitu