64464-46-6

Upstream product

• 18502-05-1 4-cyanomethylimidazole 
• 76-83-5 trityl chloride 

Downstream Products

• 151094-68-7 3-Cyano-2-methyl-3-(1-trityl-1H-imidazol-4-yl)-propionic acid ethyl ester 
• 220407-34-1 2-(1-trityl-1H-imidazol-4-yl)-acetamide 
• 64464-47-7 2-methyl-2-(1-trityl-1H-imidazol-4-yl)-propionitrile 
• 279238-10-7 C₂₈H₂₇N₃ 
• 1334541-38-6 tert-butyl (2Z)-6-[bis(tert-butoxycarbonyl)amino]-2-(1-trityl-1H-imidazol-4-yl)hex-2-enoate 
• 1334541-39-7 tert-butyl (2E)-6-[bis(tert-butoxycarbonyl)amino]-2-(1-trityl-1H-imidazol-4-yl)hex-2-enoate 
• 1334541-36-4 tert-butyl (1-trityl-1H-imidazol-4-yl)acetate 
• 168632-03-9 1-triphenylmethyl-4-imidazolyl-acetic acid 
• 173590-52-8 3-Cyano-3-methyl-3-(1-trityl-1H-imidazol-4-yl)-propionic acid methyl ester 
• 151094-14-3 4-Methyl-4-(1-trityl-1H-imidazol-4-yl)-pyrrolidin-2-one 
• 151093-87-7 3-Methyl-4-(1-trityl-1H-imidazol-4-yl)-pyrrolidin-2-one 
• 173590-43-7 4-(4-Methyl-pyrrolidin-3-yl)-1-trityl-1H-imidazole 
• 151094-15-4 4-(3-Methyl-pyrrolidin-3-yl)-1-trityl-1H-imidazole 
• 220407-36-3 3-(6-bromo-1H-indol-3-yl)-4-(1-trityl-1H-imidazol-4-yl)-pyrrole-2,5-dione 

Relevant academic research and scientific papers

Total synthesis of didemnimide A and B

The total synthesis of didemnimide A and didemnimide B, novel predator- deterrent alkaloids from the Caribbean mangrove ascidian Didemnum conchyliatum, is described.

NEW COMPOUNDS

The present invention encompasses compounds of general formula (1) wherein X and R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.