64468-29-7Relevant academic research and scientific papers
Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors
Robert, Séverine,Bertolla, Carine,Masereel, Bernard,Dogné, Jean-Michel,Pochet, Lionel
supporting information; experimental part, p. 3077 - 3080 (2009/04/07)
Recently, FXIIa was highlighted as an original attractive target for the development of new anticoagulant drugs with low rates of therapy-related hemorrhages. In this work, we describe the development of a new series of 3-carboxamide-coumarins that are the first potent and selective nonpeptidic inhibitors of FXIIa.
Photolysis of Acyl Azides Leading to Acyl Nitrenes
Elkasaby, M. A.,Noureldin, N. A.
, p. 1080 - 1081 (2007/10/02)
Photolysis of acyl azides is shown to give acyl nitrenes in the triplet state and not in the single state.The acyl nitrenes have been trapped by hydrocarbons and aniline.
