64468-56-0Relevant academic research and scientific papers
A novel asymmetric synthesis of 3-(1H-pyrrol-1-yl)-substituted β-lactams via a bismuth nitrate-catalyzed reaction
Shaikh, Aarif L.,Banik, Bimal K.
scheme or table, p. 839 - 844 (2012/06/16)
The reaction of racemic α-keto β-lactams 5a-5c with the commercially available chiral compound trans-4-hydroxy-L-proline (6) in the presence of a catalytic amount of Bi(NO3)3·5 H 2O in EtOH gave a diastereoisomer mixture o
Stereoselective synthesis of 3-alkylidene/alkylazetidin-2-ones from azetidin-2,3-diones
Tiwari, Dharmendra Kumar,Shaikh, Ashif Y.,Pavase, Laxmikant S.,Gumaste, Vikas K.,Deshmukh, Abdul Rakeeb A.S.
, p. 2524 - 2534 (2007/10/03)
Azetidin-2,3-diones have been used as synthons for the synthesis of C-3 alkylidene/alkylazetidin-2-ones. Some of the 3-alkylazetidin-2-ones are well known for their cholesterol absorption inhibitor activity. A regio and stereoselective Grignard reaction o
Azetidin-2,3-dione synthon for stereoselective synthesis of cis- and trans-C-3-alkyl/aryl azetidin-2-ones
Tiwari, Dharmendra Kumar,Gumaste, Vikas K.,Deshmukh, Abdul Rakeeb A. S.
, p. 115 - 122 (2007/10/03)
1,4-Bis-(4-methoxyphenyl)azetidin-2,3-dione has been prepared and used as a synthon for the stereoselective synthesis of C-3-alkyl/aryl azetidin-2-ones. Some of these are well known for their cholesterol absorption inhibitor activity. A regioselective Gri
Addition of α-bromoesters to Azetidine-2,3-diones Promoted by Zinc-Trimethylchlorosilane: A General Synthesis of 3-trimethylsilyloxyazetidin-2-ones and α-Alkylidene β-lactams.
Palomo, Claudio,Aizpurua, Jesus M.,Lopez, M. Concepcion,Aurrekoetxea, Natalia,Oiarbide, Mikel
, p. 6425 - 6428 (2007/10/02)
A convenient procedure for the preparation of α-alkylidene β-lactams from monocyclic azetidine-2,3-diones by means of the Reformatsky reaction is described.
STEREOSELECTIVE ANNELATION OF TRIMETHYLSILOXYACETIC ACIDS AND IMINES INTO 3-HYDROXY-β-LACTAMS
Cossio, Fernando P.,Palomo, Claudio
, p. 4239 - 4242 (2007/10/02)
Stereoselective synthesis of variously substituted 3-hydroxy-β-lactams can be achieved by the annelation of Schiff bases with trimethylsiloxyacetic acids promoted by phenyl dichlorophosphate reagent.A potential synthesis of N-unsubstituted β-lactams is ma
