64473-02-5

Basic information

• Product Name: 2-Propenoic acid, 2-bromo-, phenylmethyl ester
• CAS NO: 64473-02-5
• Molecular Formula: C10H9BrO2
• Molecular Weight: 241.084
• Mol File: 64473-02-5.mol

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-bromo-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-bromo-, phenylmethyl ester(64473-02-5)
• EPA Substance Registry System: 2-Propenoic acid, 2-bromo-, phenylmethyl ester(64473-02-5)

Safety Data

• Hazardous Substances Data: 64473-02-5(Hazardous Substances Data)

Upstream product

• 10443-65-9 2-bromo-2-propenoic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 97962-02-2 (1R,2R)-1-Benzyloxymethyl-2-bromo-cyclopropane-1,2-dicarboxylic acid dibenzyl ester 
• 37631-80-4 benzyl [3'R,4'R]2-bromo-3(4'-n-butyldithio-3'-phenylacetamidoazetidin-2'-on-1'yl) propionate 
• 1402585-64-1 benzyl 2-(4-((2-(benzyloxy)ethoxy)methyl)-3-fluorophenyl)acrylate 
• 1402585-48-1 benzyl 2-(4-(1-(tert-butyldimethylsilyloxy)cyclopropyl)-3-fluorophenyl)acrylate 
• 1255041-85-0 benzyl 2-(3-fluoro-4-((2-methoxyethoxy)methyl)phenyl)acrylate 
• 1018052-33-9 2-benzyloxymethyl-2-hydroxymethyl-1-methylenecyclopropane 
• 72237-07-1 (3S,5R,6R)-benzyl 6-(N-nitrobenzyloxycarbonyl-D-α-aminophenylacetamido)bisnorpenicillanate 
• 51989-06-1 (3S,5R,6R)-benzyl 6-aminobisnorpenicillanate 
• 51989-07-2 (3S,5R,6R)-benzyl 6-phenoxyacetamidobisnorpenicillanate 
• 74740-85-5 2-[(2R,3R)-4-Oxo-3-(2-phenoxy-acetylamino)-azetidin-2-ylsulfanyl]-acrylic acid benzyl ester 
• 74732-83-5 2-Bromo-3-[(2R,3R)-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-2-ylsulfanyl]-propionic acid benzyl ester 
• 64473-04-7 (2R,5R,6R)-benzyl 6-phenoxyacetamidopenam-2-carboxylate 
• 64473-03-6 (3R,5R,6R)-benzyl 6-phenoxyacetamidobisnorpenicillanate 

Relevant articles and documents

SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II

The invention relates to oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN O-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted pyrazolyl-based carboxamide and urea derivatives of formula (Q) as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Robust eco-friendly protocol for the preparation of γ-hydroxy- α,β-acetylenic esters by sequential one-pot elimination-addition of 2-bromoacrylates to aldehydes promoted by LTMP in 2-MeTHF

An efficient and widely applicable preparation of γ-hydroxy-α, β-acetylenic esters is described by means of a one-pot dehydrobromination of a 2-bromoacrylate ester with LTMP followed by the electrophilic addition of the transient propiolate to different aldehydes in the eco-friendly solvent 2-MeTHF. The Royal Society of Chemistry 2012.

SUBSTITUTED PHENYLLUREAS AND PHENYLAMIDES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted phenylureas and phenylamides of formula (I), to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions.

The Chemistry of 4-Mercaptoazetidine-2-ones. Part 2. Synthesis of Bisnorpenicillins

Reaction of the 4-mercaptoazetidinone (2) with benzyl 2-bromoacrylate gave the C-3-epimeric bisnorpenicillin esters (6b) and (7b).Standard procedures were used to convert the ester (6b) into bisnorpenicillin V (3) and bisnorampicillin (15).By contrast (2)