64490-46-6 Usage
Uses
Used in Pharmaceutical Industry:
1-(chloromethyl)-2-iodo-3,4,5-trimethoxybenzene is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure, including the iodo and chloromethyl groups, allows for the creation of a wide range of medicinal compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(chloromethyl)-2-iodo-3,4,5-trimethoxybenzene is utilized as a starting material for the development of new agrochemicals. Its structural features facilitate the production of innovative compounds that can be used in agriculture for pest control, crop protection, and other related applications.
Used in Organic Synthesis:
1-(chloromethyl)-2-iodo-3,4,5-trimethoxybenzene is employed as a versatile building block in organic synthesis. Its functional groups enable the formation of complex organic molecules, which can be further modified for various applications in research and industry.
Used in Research and Development:
1-(chloromethyl)-2-iodo-3,4,5-trimethoxybenzene is also used in research and development settings, where its unique properties can be explored for potential new applications. The trimethoxy groups may influence the compound's reactivity, solubility, and other characteristics, making it an interesting subject for scientific investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 64490-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,4,9 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 64490-46:
(7*6)+(6*4)+(5*4)+(4*9)+(3*0)+(2*4)+(1*6)=136
136 % 10 = 6
So 64490-46-6 is a valid CAS Registry Number.
64490-46-6Relevant academic research and scientific papers
Cycloadditions of 4-pyrones. An approach to colchicine
McBride,Garst
, p. 2839 - 2854 (2007/10/02)
The 4-pyrone, [5-acetoxy-4-oxo-4H-pyran-2-yl]carbonyl chloride was coupled with the malonate anion of bis(2,2,2-trichloroethyl) 2-ethenyl-3,4,5-trimethoxybenzylpropanedioate and analogs thereof. These adducts then underwent intramolecular thermal cyclizations (61-100% yield) to form the two fused seven member rings of the carbon skeleton of colchicine. The malonate moiety was deprotected and decarboxylated quantitatively to provide the desired ring system which contained a bridging ether, from C7a to C11 in the C ring, and a ketone at the 7 position. Removal of the bridging ether as H2O would yield the desired tropolone. Our attempts to remove the ether bridge were unsuccessful.
