64496-72-6Relevant academic research and scientific papers
From glycerol to chlorohydrin esters using a solvent-free system. Microwave irradiation versus conventional heating
Escribà, Marc,Eras, Jordi,Duran, Miquel,Simon, Sílvia,Butchosa, Cristina,Villorbina, Gemma,Balcells, Mercè,Canela, Ramon
experimental part, p. 10370 - 10376 (2010/02/27)
Esterification-chlorination of glycerol provides chlorohydrin esters in high yields. A ratio of reagents close to equivalence can be used, so that atom economy of the reaction is optimized. The reaction can be carried out using either classical or microwa
A tandem Finkelstein-rearrangement-elimination reaction: a straightforward synthetic route to allyl esters
Eras, Jordi,Escribà, Marc,Villorbina, Gemma,Oromí-Farrús, Mireia,Balcells, Mercè,Canela, Ramon
experimental part, p. 4866 - 4870 (2009/10/02)
Allyl esters can be obtained by a Finkelstein-rearrangement-elimination reaction of 2-chloro-1-(chloromethyl)ethyl esters induced by NaI. Sodium iodide can be used below equivalence using a reductive agent as sodium thiosulfate. High yields are obtained with most of the diverse esters studied. The method described avoids the use of allyl alcohol as a reagent. 2-Chloro-1-(chloromethyl)ethyl esters are prepared from glycerol, the main by-product of biodiesel industry. The effectiveness of iodine as reagent to hydrolyze allyl esters is also confirmed.
Combining AlCl3·6H2O and an ionic liquid to prepare chlorohydrin esters from glycerol
Villorbina, Gemma,Tomàs, Albert,Escribà, Marc,Oromí-Farrús, Mireia,Eras, Jordi,Balcells, Mercè,Canela, Ramon
experimental part, p. 2828 - 2830 (2009/09/30)
We describe here the first example in which glycerol has been transformed into chlorohydrin esters using an ionic liquid and hydrated aluminium chloride. The method avoids using Crown-18 ether, which was needed to obtain a similar yield when KCl was used.
