64496-72-6Relevant academic research and scientific papers
Combining AlCl3·6H2O and an ionic liquid to prepare chlorohydrin esters from glycerol
Villorbina, Gemma,Tomàs, Albert,Escribà, Marc,Oromí-Farrús, Mireia,Eras, Jordi,Balcells, Mercè,Canela, Ramon
experimental part, p. 2828 - 2830 (2009/09/30)
We describe here the first example in which glycerol has been transformed into chlorohydrin esters using an ionic liquid and hydrated aluminium chloride. The method avoids using Crown-18 ether, which was needed to obtain a similar yield when KCl was used.
From glycerol to chlorohydrin esters using a solvent-free system. Microwave irradiation versus conventional heating
Escribà, Marc,Eras, Jordi,Duran, Miquel,Simon, Sílvia,Butchosa, Cristina,Villorbina, Gemma,Balcells, Mercè,Canela, Ramon
experimental part, p. 10370 - 10376 (2010/02/27)
Esterification-chlorination of glycerol provides chlorohydrin esters in high yields. A ratio of reagents close to equivalence can be used, so that atom economy of the reaction is optimized. The reaction can be carried out using either classical or microwa
A tandem Finkelstein-rearrangement-elimination reaction: a straightforward synthetic route to allyl esters
Eras, Jordi,Escribà, Marc,Villorbina, Gemma,Oromí-Farrús, Mireia,Balcells, Mercè,Canela, Ramon
experimental part, p. 4866 - 4870 (2009/10/02)
Allyl esters can be obtained by a Finkelstein-rearrangement-elimination reaction of 2-chloro-1-(chloromethyl)ethyl esters induced by NaI. Sodium iodide can be used below equivalence using a reductive agent as sodium thiosulfate. High yields are obtained with most of the diverse esters studied. The method described avoids the use of allyl alcohol as a reagent. 2-Chloro-1-(chloromethyl)ethyl esters are prepared from glycerol, the main by-product of biodiesel industry. The effectiveness of iodine as reagent to hydrolyze allyl esters is also confirmed.
