644970-44-5

Upstream product

• 644969-50-6 methyl 2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-[(4-methoxybenzyl)oxy]benzoate 
• 644969-49-3 C₁₉H₂₀O₆ 
• 148965-89-3 methyl 2-hydroxy-4-(4-methoxy-benzyloxy)benzoate 
• 644970-45-6 C₃₄H₄₀ClN₃O₇ 

Relevant academic research and scientific papers

Design, synthesis and structure activity relationships of spirocyclic compounds as potent CCR1 antagonists

A series of CCR1 antagonists based upon spirocyclic compounds 1b and 2b were synthesised in which substituted aniline moiety was replaced with substituted benzamides. In vitro data revealed that CCR1 potency could be retained in such compounds.