644969-50-6

Basic information

• Product Name: methyl 2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-[(4-methoxybenzyl)oxy]benzoate
• Synonyms: methyl 2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-[(4-methoxybenzyl)oxy]benzoate
• CAS NO: 644969-50-6
• Molecular Weight: 568.066
• Mol File: 644969-50-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-[(4-methoxybenzyl)oxy]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-[(4-methoxybenzyl)oxy]benzoate(644969-50-6)
• EPA Substance Registry System: methyl 2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-[(4-methoxybenzyl)oxy]benzoate(644969-50-6)

Safety Data

• Hazardous Substances Data: 644969-50-6(Hazardous Substances Data)

Upstream product

• 644967-79-3 5-chlorospiro[1-benzofuran-2,4'-piperidine]-1'-carboxylic acid 1,1-dimethylethyl ester 
• 1996-30-1 2-bromo-4-chloro-1-fluorobenzene 
• 147804-30-6 1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester 
• 148965-89-3 methyl 2-hydroxy-4-(4-methoxy-benzyloxy)benzoate 
• 644969-49-3 C₁₉H₂₀O₆ 
• 71916-97-7 5-chloro-2,3-dihydrospiro 

Downstream Products

• 644971-12-0 C₂₇H₃₃ClN₂O₆ 
• 1439403-45-8 C₃₆H₄₄ClN₃O₆ 
• 644970-44-5 C₂₆H₃₂ClN₃O₆ 
• 644970-45-6 C₃₄H₄₀ClN₃O₇ 

Relevant articles and documents

Design, synthesis and structure activity relationships of spirocyclic compounds as potent CCR1 antagonists

A series of CCR1 antagonists based upon spirocyclic compounds 1b and 2b were synthesised in which substituted aniline moiety was replaced with substituted benzamides. In vitro data revealed that CCR1 potency could be retained in such compounds.