644981-80-6

Basic information

• Product Name: 1-Boc-4-(4-fluorophenyl)-4-piperidineacetic acid
• Synonyms: 1-Boc-4-(4-fluorophenyl)-4-piperidineacetic acid
• CAS NO: 644981-80-6
• Molecular Formula: C₁₈H₂₄FNO₄
• Molecular Weight: 337.3858632
• Mol File: 644981-80-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Boc-4-(4-fluorophenyl)-4-piperidineacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-4-(4-fluorophenyl)-4-piperidineacetic acid(644981-80-6)
• EPA Substance Registry System: 1-Boc-4-(4-fluorophenyl)-4-piperidineacetic acid(644981-80-6)

Safety Data

• Hazardous Substances Data: 644981-80-6(Hazardous Substances Data)

Usage

Structure

Contains a piperidine ring and a carboxylic acid functional group

Functional Groups

Piperidine ring, carboxylic acid, and Boc (tert-butoxycarbonyl) protecting group

Derivative

A derivative of piperidine

Stability

Increased stability due to the presence of the Boc protecting group

Selectivity

Allows for selective reactions to occur

Applications

Used as a building block in organic synthesis for the preparation of various pharmaceutical compounds

Potential Applications

Drug development and medicinal chemistry

Biological Activity

Can be used to synthesize biologically active compounds for the treatment of various diseases

Upstream product

• 644981-79-3 4-[(1-cyano-1-ethoxycarbonyl)-methyl]-4-(4-fluorophenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 644982-86-5 1-piperidinecarboxylic acid, 4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-4-(4-fluorophenyl)-1,1-dimethyl ester 

Downstream Products

• 644982-48-9 1,1-dimethylethyl 4-{2-[{[3,5-bis(trifluoromethyl)phenyl]methyl}(methyl)amino]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate 
• 644982-31-0 4-({[1-(S)-1-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-methyl-carbamoyl}-methyl)-4-(4-fluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 644982-33-2 4-({[1-(3,5-dibromo-phenyl)-ethyl]-methyl-carbamoyl}-methyl)-4-(4-fluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 644982-34-3 4-({[1-(3,5-dibromo-phenyl)-ethyl]-methyl-carbamoyl}-methyl)-4-(4-fluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester (enantiomer 2) 
• 644982-29-6 4-{[(3,5-dibromobenzyl)methylcarbamoyl]methyl}-4-(4-fluorophenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 644982-36-5 4-{[1-(3,5-dichloro-phenyl)-ethylcarbamoyl]-methyl}-4-(4-fluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 644982-51-4 4-({[1-(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-methyl-carbamoyl}-methyl)-4-(4-fluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 644982-49-0 1,1-dimethylethyl 4-(2-{[1-(3,5-dibromophenyl)-1-methylethyl]amino}-2-oxoethyl)-4-(4-fluorophenyl)-1-piperidinecarboxylate 
• 852880-39-8 1,1-dimethylethyl 4-(4-fluorophenyl)-4-[2-(methyloxy)-2-oxoethyl]-1-piperidinecarboxylate 

Relevant articles and documents

BETA-LACTAMS FOR TREATMENT OF CNS DISORDERS

The present invention relates to novel compounds of formula (I) wherein ---- represents a single or a double bond; R represents a radical selected from formulae i), ii), iii) and iv) in which R1 is halogen, cyano, C1-4 alkyl, C1