645-15-8

Basic information

• Product Name: Bis(4-nitrophenyl) phosphate
• Synonyms: BIS(4-NITROPHENYL)PHOSPHORIC ACID;Bis(4-nitrophenyl)hydrogen phosphate;BIS(4-NITROPHENYL) PHOSPHATE;BIS(P-NITROPHENYL)PHOSPHATE;DI-P-NITROPHENYLPHOSPHORIC ACID;DI-4-NITROPHENYL HYDROGENPHOSPHATE;BNPP;Di-p-nitrophenyl phosphate
• CAS NO: 645-15-8
• Molecular Formula: C₁₂H₉N₂O₈P
• Molecular Weight: 340.18
• EINECS: 211-434-7
• Product Categories: Aromatics Compounds;Aromatics;Phosphorylating and Phosphitylating Agents
• Mol File: 645-15-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 172-175 °C(lit.)
• Boiling Point: 545.7 °C at 760 mmHg
• Flash Point: 283.8 °C
• Appearance: White-like or yellowish crystalline powder
• Density: 1.614 g/cm³
• Vapor Pressure: 9.64E-13mmHg at 25°C
• Storage Temp.: -20°C Freezer
• PKA: 1.04±0.50(Predicted)
• Water Solubility: almost transparency
• CAS DataBase Reference: Bis(4-nitrophenyl) phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(4-nitrophenyl) phosphate(645-15-8)
• EPA Substance Registry System: Bis(4-nitrophenyl) phosphate(645-15-8)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: TB8260000
• Hazardous Substances Data: 645-15-8(Hazardous Substances Data)

Usage

Chemical Properties

Bis(4-nitrophenyl) phosphate is Light Brown Powder

Uses

Different sources of media describe the Uses of 645-15-8 differently. You can refer to the following data:
1. Bis(4-nitrophenyl) phosphate(BNPP) has been used as substrate to determine the enzyme activity of root phosphodiesterases of wetland plants. BNPP has been used to study the mechanism of cleavage of BNPP using oxamido-bridged dinuclear copper(II) complexes as catalysts.
2. Inhibitor of enzyme. It is used for Phosphodiesterase Substrate.

InChI:InChI=1/C12H9N2O8P/c15-13(16)9-1-5-11(6-2-9)21-23(19,20)22-12-7-3-10(4-8-12)14(17)18/h1-8H,(H,19,20)/p-1

Upstream product

• 100-02-7 4-nitro-phenol 
• 838-85-7 diphenyl hydrogen phosphate 
• 3871-20-3 tris(p-nitrophenyl)phosphate 
• 2015-56-7 diphenylphosphoroamidate 
• 7697-37-2 nitric acid 

Downstream Products

• 72011-67-7 Phosphoric acid 4-nitro-phenyl ester phenethyl ester 
• 100-02-7 4-nitro-phenol 
• 330-13-2 mono-p-nitrophenyl phosphate 
• 41086-74-2 2-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methoxycarbonyl-1,2,3-triazole 
• 31843-61-5 methyl 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-v-triazole-4-carboxylate 
• 637743-35-2 [Cu(tris(2-pyridylmethyl)amine)(bis(p-nitrophenylphosphate)](ClO₄) 
• 1228321-62-7 C₁₇H₁₅N₂O₁₀P 
• 86119-84-8 phosphoric acid 
• 6546-97-0 bis(4-nitrophenyl) phosphorochloridate 
• 72011-66-6 phosphoric acid 2-methoxy-ethyl ester 4-nitro-phenyl ester 
• 71465-03-7 Octadecanoic acid 2-[bis-(4-nitro-phenoxy)-phosphoryloxy]-1-octadecanoyloxymethyl-ethyl ester 
• 17659-67-5 ethyl p-nitrophenyl phosphate 
• 72779-21-6 phosphoric acid 4-nitro-phenyl ester prop-2-ynyl ester 
• 111269-96-6 O¹,O²-isopropylidene-O³,O⁵-(4-nitro-phenoxyphosphoryl)-α-D-xylofuranose 

Relevant articles and documents

Pentacoordinate Nickel(II) Complexes Double Bridged by Phosphate Ester of Phosphinate Ligands: Spectroscopic, Structural, Kinetic and Magnetic Studies

The bis(phosphatediester)-bridged complexes [{Ni([12]aneN 3)(μ-O2P(OR)2)}2](PF 6)2 {[12]aneN3= Me3[12]aneN 3, 2,4,4-trimethyl-1,5,9-triazacyclododec-1-ene; R=Me (1), Bu (2), Ph (3), Ph-4-NO2 (4); [12]aneN3= Me 4[12]aneN3, 2,4,4,9-tetramethyl-1,5,9-triazacyclododec-1-ene; R=Me (5), Bu (6), Ph (7), Ph-4-NO2 (8)} were prepared by hydrolysis of the phosphate triester with the hydroxo complex [{Ni([12]aneN3)(μ-OH)} 2](PF6)2 or by acid-base reaction of the dialkyl or diaryl phosphoric acid and the above hydroxo complex. The acid-base reaction was also used to synthesise the phosphinate-bridged complexes [{Ni([12]aneN3)(μ-O2PR2)} 2](PF6)2 {[12]aneN3=Me 3[12]aneN3, R=Me (9), Ph (10); [12]aneN 3=Me4[12]aneN3, R=Me (11), Ph (12)}. The molecular structures of complexes 2, 3 and 12 were established by single crystal X-ray diffraction studies. The eight-membered rings defined by the nickel atoms and the bridging ligands show distorted twist-boat, chair and boat-boat conformations in 2, 3 and 12, respectively. The experimental susceptibility data for compounds 2, 3 and 12 were fitted by least-squares methods to the analytical expression given by Ginsberg. The best fit was obtained with values of J= -0.11 cm-1, D=-9.5 cm-1 and g=2.20 for 2; J=-0.97 cm-1, D=-9.3 cm-1 and g=2.21 for 3; and J=-0.14 cm-1, D=-11.9 cm-1 and g=2.195 for 12. The magnetic-exchange pathways must involve the phosphate/phosphinate bridges, because these favour antiferromagnetic interactions. The observation of a higher exchange parameter for compound 3 is a consequence of a favourable disposition of the O-P-O bridges. The kinetics for the hydrolysis of TNP (tris(4-nitrophenyl)phosphate) with the dinuclear nickel(II) hydroxo complex [{Ni(Me3[12]aneN3)(μ-OH)}2]-(PF 6)2 was studied by UV-visible spectroscopy. The proposed mechanism for TNP-promoted hydrolysis can be described as one-substrate/two-product, and can be fitted to a Michaelis-Menten equation.

Photo-enhanced hydrolysis of bis(4-nitrophenyl) phosphate using Cu(ii) bipyridine-capped plasmonic nanoparticles

We show that the hydrolysis of bis(4-nitrophenyl) phosphate by a Cu(ii) bipyridine complex was enhanced by 1000-fold when covalently attached to 10 nm gold nanoparticles (AuNP) and irradiated with a 120 mW green laser at 532 nm when compared to an unsuppo

Regulation of the hydrolytic activity of Mg2+-dependent phosphatase models by intramolecular NH···O hydrogen bonds

Magnesium-dependent phosphatase models containing intramolecular NH···O hydrogen bonds were synthesized and structurally characterized by X-ray analysis. The Mg-O bond distances varied with the mode of the hydrogen bonds. 1H NMR spectra in nonp