64505-66-4Relevant academic research and scientific papers
Photoinduced EDA Complexes Enabled Radical Tandem Cyclization/Arylation of Unactivated Alkene with 2-Amino-1,4-naphthoquinones
Sun, Bin,Shi, Xiayue,Zhuang, Xiaohui,Huang, Panyi,Shi, Rongcheng,Zhu, Rui,Jin, Can
, p. 1862 - 1867 (2021)
A visible-light-induced radical tandem cyclization/arylation between 2-amino-1, 4-naphthoquinone and N-allyl-2-bromo-2,2-difluoroacetamides has been developed without an external photocatalyst. The transformation could be carried out at room temperature a
Synthesis, antibacterial and antifungal activity of 2-amino-1,4- naphthoquinones using silica-supported perchloric acid (HClO4- SiO2) as a mild, recyclable and highly efficient heterogeneous catalyst
Sharma, Upendra,Katoch, Deepali,Sood, Swati,Kumar, Neeraj,Singh, Bikram,Thakur, Archana,Gulati, Arvind
, p. 1431 - 1440 (2014/01/06)
Perchloric acid adsorbed on silica gel (1 mol%) has been found to be an efficient and recyclable heterogeneous catalyst for rapid conjugate addition of primary and secondary amines with 1,4-naphthoquinone to afford 2-amino-1,4-naphthoquinones under ultrasonication in moderate to high yields without using any solvent. The compounds tested for in vitro antimicrobial activity have shown high antibacterial activity against Gram positive bacteria Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus as compared to Gram negative bacteria Burkholderia cepacia, Escherichia coli, Enterobacter cloacae, Klebseilla pneumoniae and Pseudomonas aeruginosa. High antifungal activity has been observed against Candida albicans and Issatchenkia orientalis for all the compounds.
