64507-20-6

Upstream product

• 13051-21-3 3-methoxy-2,2-dimethyl-3-oxopropanoic acid 

Downstream Products

• 194031-19-1 N-Allyl-2,2-dimethyl-N-phenyl-malonamic acid methyl ester 
• 194031-17-9 (E)-3-[2-(2-Methoxycarbonyl-2-methyl-propionylamino)-phenyl]-acrylic acid ethyl ester 
• 194031-13-5 2,2-Dimethyl-malonic acid 2-((E)-2-ethoxycarbonyl-vinyl)-phenyl ester methyl ester 
• 194031-18-0 N-But-3-enyl-2,2-dimethyl-N-phenyl-malonamic acid methyl ester 
• 194031-15-7 2,2-Dimethyl-malonic acid 2-((E)-2-ethoxycarbonyl-vinyl)-5-methoxy-phenyl ester methyl ester 
• 194031-14-6 2,2-Dimethyl-malonic acid 2-((E)-2-ethoxycarbonyl-vinyl)-5-methyl-phenyl ester methyl ester 
• 194031-20-4 (E)-5-[(2-Methoxycarbonyl-2-methyl-propionyl)-phenyl-amino]-pent-2-enoic acid ethyl ester 
• 194031-21-5 (E)-4-[(2-Methoxycarbonyl-2-methyl-propionyl)-phenyl-amino]-but-2-enoic acid ethyl ester 
• 64507-21-7 3-[4-(2-Acetylamino-ethyl)-phenyl]-2,2-dimethyl-3-oxo-propionic acid methyl ester 

Relevant academic research and scientific papers

Dimethyl 2,2,6,6-tetramethyl-3,5-dioxo-4-oxaheptanedioate

The title compound, C12H18O7, crystallizes with the anhydride moiety non-planar and in the trans,trans conformation. The stability of this compound suggests that quaternary C atoms attached to carbonyl C atoms have a stabilizing influence on acyclic anhydride compounds.

Synthesis of ω-substituted alkanethiols and (bromomethyl)methylthiomalonates

Several multifunctional derivatives of methylthiomalonic acid (= 2-(thiocarboxy)acetic acid), i.e. 20a,b, 21, 22a,b, and 24, were prepared from thiols bearing a functionalized head group, i.e. from 9a,b, 12, and 16d,f (Schemes 4 and 5). The association constants of the two dithio podands 8b and 11 with K+ were determined.