64507-38-6Relevant academic research and scientific papers
BENZOPYRAZOLE COMPOUND USED AS RHO KINASE INHIBITOR
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Paragraph 0414-0416, (2021/02/25)
The invention relates to a benzopyrazole compound used as RHO kinase inhibitor, a pharmaceutical composition and uses thereof for preparing an RHO kinase inhibiting drug, and more specifically to said compound of formula (I-1), a pharmaceutically acceptable salt and isomer thereof.
Method for preparing 8-quinoline carboxylic acid and derivatives of 8-quinoline carboxylic acid
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Paragraph 0028-0029, (2021/01/15)
The invention discloses a method for preparing 8-quinoline carboxylic acid and derivatives thereof, which comprises the following steps: by using a compound I as a raw material, reacting with an oxidant at the temperature of 50-150 DEG C under normal pressure in a solvent under the action of a Cu-Co-X ternary composite catalyst to obtain a compound II; according to the method, the efficient Cu-Co-X ternary composite catalyst is adopted, the reaction is carried out at the temperature of 50-150 DEG C under normal pressure, the reaction condition is mild, the oxidation yield is remarkably increased, near-zero emission of three wastes is realized, the pollution problem is effectively solved, and the production cost is greatly reduced.
PLANT GROWTH REGULATOR
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Paragraph 0047, (2018/05/24)
PROBLEM TO BE SOLVED: To provide a plant growth regulator. SOLUTION: The plant growth regulator comprises a compound represented by general formula 1, or a salt or ester thereof. [In the formula, (A1-A2-A3-A4) is (N=CH-CH=CH) or (NH-CH2-CH2-CH2); R1 and R2 are each independently H, an alkyl group or a halogen atom; and R3 is a hydroxyl group or an alkoxy group.] SELECTED DRAWING: None COPYRIGHT: (C)2018,JPO&INPIT
Hypoglycemic quinoline 8 carboxamidoalkyl benzenesulfonamide derivatives
Weyer,Aumuller,Bander,Heerdt,Pfaff,Schweitzer,Weber
, p. 269 - 275 (2007/10/08)
The paper reports on acylaminoalkylbenzenesulfonyl ureas, sulfonylsemicarbazides and sulfonylaminopyrimidines, which carry as acylrest the rest of the quinoline 8 carboxylic acid, possibly substituted. Pharmacological tests reveal that the compounds have a strong blood sugar lowering effects.
