6451-71-4Relevant academic research and scientific papers
Synthesis of Heterocycles via Lactones: Part VI Condensation of Bromo Esters with β-Phenethylamines, a New Route to Berbines: Synthesis of (+/-)-Xylopinine, (+/-)-Scoulerine, Isocoptisine and Pseudoepitetrahydroberberine
Pandey, G. D.,Tiwari, K. P.
, p. 272 - 275 (2007/10/02)
A new route involving the generation of a tricyclic lactam intermediate in one-step has been developed for the synthesis of 2,3,10,11-tetraoxygenated berbine alkaloids.Three such alkaloids have been synthesized besides scoulerine which is 2,9-dihydroxy-3,10-dimethoxyberbine (11).
