72584-82-8

Upstream product

• 6451-76-9 7-Methoxy-8-benzyloxy-3-isochromanone 

Downstream Products

• 6451-70-3 2-(3'-Methoxy-4'-benzyloxy-β-phenethyl)-7-methoxy-8-benzyloxy-1,2,3,4-tetrahydro-3-isoquinolone 
• 791535-84-7 2,9-Bis-benzyloxy-3,10-dimethoxy-5,6,8,13-tetrahydro-isoquino[3,2-a]isoquinolinylium 
• 6451-71-4 O,O-Dibenzylscoulerine 

Relevant academic research and scientific papers

Synthesis of Heterocycles via Lactones: Part VI Condensation of Bromo Esters with β-Phenethylamines, a New Route to Berbines: Synthesis of (+/-)-Xylopinine, (+/-)-Scoulerine, Isocoptisine and Pseudoepitetrahydroberberine

A new route involving the generation of a tricyclic lactam intermediate in one-step has been developed for the synthesis of 2,3,10,11-tetraoxygenated berbine alkaloids.Three such alkaloids have been synthesized besides scoulerine which is 2,9-dihydroxy-3,10-dimethoxyberbine (11).