64518-82-7

Upstream product

• 1094338-77-8 C₁₆H₁₇NO₃ 
• 150-13-0 4-amino-benzoic acid 
• 591-31-1 3-methoxy-benzaldehyde 

Downstream Products

• 1246560-50-8 [4-(3-methoxybenzylamino)phenyl](4-methoxyphenyl)methanone 
• 1246560-46-2 [4-(3-methoxybenzylamino)phenyl]-p-tolyl-methanone 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of benzylamino-methanone based cholesteryl ester transfer protein inhibitors

Cholesteryl ester transfer protein (CETP) is a glycoprotein involved in transporting lipoprotein particles and neutral lipids between high-density lipoprotein (HDL) and low density lipoproteins (LDL) and therefore its a proper target for treating dyslipidemia and related disorders. Guided by our previosuly-reported pharmacophore and QSAR models for CETP inhibition, we synthesized and bioassayed a series of benzylamino-methanones. The most potent illustrated 30% CETP inhibition at 10 μM.