64519-09-1

Basic information

• Product Name: Benzaldehyde, 3-chloro-4-(dimethylamino)-
• CAS NO: 64519-09-1
• Molecular Formula: C9H10ClNO
• Molecular Weight: 183.637
• Mol File: 64519-09-1.mol

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 3-chloro-4-(dimethylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3-chloro-4-(dimethylamino)-(64519-09-1)
• EPA Substance Registry System: Benzaldehyde, 3-chloro-4-(dimethylamino)-(64519-09-1)

Safety Data

• Hazardous Substances Data: 64519-09-1(Hazardous Substances Data)

Upstream product

• 698-01-1 1-chloro-2-(dimethylamino)benzene 
• 507-40-4 tert-butylhypochlorite 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 34328-61-5 3-Chloro-4-fluorobenzaldehyde 
• 124-40-3 dimethyl amine 

Downstream Products

• 64518-72-5 4-(3-Chloro-4-dimethylamino-benzylamino)-benzoic acid 

Relevant articles and documents

In situ Generation of Hypervalent Iodine Reagents for the Electrophilic Chlorination of Arenes

Efficient metal-free methods for the electrophilic chlorination of arenes using PIFA and simple chlorine sources are reported. The in situ formation of PhI(Cl)OCOCF3 from PIFA and KCl is proposed, which resulted in a chlorinating species for moderately activated arenes. Moreover, the in situ formation of PhICl2 from PIFA and TMSCl resulted in an excellent approach for the chlorination of a great variety of arenes (20 examples) in high yields, even when working on a multigram scale.

Aggregation-induced emission enhancement in halochalcones

A family of push-pull fluorophores, consisting of a chalcone core decorated with electron-donating substituents and halogen atoms, was designed and synthesized. Luminescence studies were performed in solution, aggregate form and in the solid state. Although some compounds are only weakly fluorescent in solution, all are emissive in the solid state showing aggregation-induced emission enhancement. In the crystalline state, the halogen atoms are not involved in halogen bonds but their presence strongly influences the aggregation-induced emission properties of the fluorophores.

Supramolecular organization of bis(3-halo-4-dimethylaminobenzylidene) hydrazines

Bis(3-bromo-4-dimethylaminobenzylidene)hydrazine and bis(3-chloro-4- dimethylaminobenzylidene)hydrazine have been synthesized, and their monoclinic crystal structures solved in space group P21/c. For the bromo derivative at 150 K, a = 10.4505(2

A facile, regioselective and controllable bromination of aromatic amines using a CuBr2/Oxone system

A combination of cupric bromide and Oxone serves as a facile, mild and effective reagent for the bromination of aromatic amines. Primary, secondary and tertiary aromatic amines are all suitable substrates. The reaction possesses high regioselectivity and functional group tolerance, and mono- and multi-brominated products can be obtained controllably in moderate to excellent yields. The Royal Society of Chemistry 2013.

ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF

Compounds that are VLA-1 integrin antagonists are disclosed. Also disclosed are compositions containing such compounds, and methods of using such compounds in treating diseases mediated, at least in part, by the VLA-1 integrin.