64519-22-8 Usage
General Description
NORCIMIFUGIN is a natural compound isolated from the oriental medicinal plant, Chelidonium majus. It has been found to exhibit various pharmacological properties, including anti-inflammatory, anti-cancer, and anti-viral activities. NORCIMIFUGIN has shown potential in inhibiting the growth of cancer cells, including breast cancer, prostate cancer, and leukemia cells. Additionally, it has been reported to have anti-inflammatory effects by suppressing the production of pro-inflammatory cytokines. NORCIMIFUGIN also possesses antiviral properties, as it has been shown to inhibit the replication of the hepatitis B virus. Overall, NORCIMIFUGIN is a promising compound with potential therapeutic applications in cancer treatment, inflammation, and viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 64519-22-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,5,1 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64519-22:
(7*6)+(6*4)+(5*5)+(4*1)+(3*9)+(2*2)+(1*2)=128
128 % 10 = 8
So 64519-22-8 is a valid CAS Registry Number.
64519-22-8Relevant articles and documents
An antiinflammatory active furochromone, norcimifugin from Cimicifuga foetida: Isolation, characterization, total synthesis and antiinflammatory activity of its Analogues
Lal, Bansi,Kansal,Singh, Rekha,Sankar,Kulkarni, Anagha S.,Gund, Vitthal G.
, p. 881 - 893 (2007/10/03)
In the course of our investigation to isolate the non-steroidal antiinflammatory active (NSAIA) lead molecules from the plants, 1 [(2S)-4-hydroxy-7-hydroxymethyl-2-(1-hydroxy-l-methylethyl)-2,3-dihydro-5H- oxolo[3′2′:4,5]-benzo [b]oxin-5-one also called as norcimifugin] has been isolated from the dichloromethane extract of rhizomes of Cimicifuga foetida. Characterization, total synthesis and antiinflammatory activity of 1 are reported. Alkyl, ester, carbamate, amine derivatives of 1 have been synthesized and their antiinflammatory activity assessed. Norcimifugin displayed antiinflammatory activity in the carrageenin induced paw edema model (50.4% inhibition at 50 mg/kg, p.o.).
