64519-22-8 Usage
Uses
Used in Cancer Treatment:
NORCIMIFUGIN is used as an anti-cancer agent for its ability to inhibit the growth of cancer cells, particularly breast, prostate, and leukemia cells. Its potential therapeutic applications in cancer treatment make it a valuable compound for further research and development.
Used in Anti-Inflammatory Applications:
NORCIMIFUGIN is used as an anti-inflammatory agent for its capacity to suppress the production of pro-inflammatory cytokines. This property makes it a promising candidate for the treatment of inflammatory conditions.
Used in Antiviral Applications:
NORCIMIFUGIN is used as an antiviral agent for its ability to inhibit the replication of the hepatitis B virus. This characteristic highlights its potential in the development of treatments for viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 64519-22-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,5,1 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64519-22:
(7*6)+(6*4)+(5*5)+(4*1)+(3*9)+(2*2)+(1*2)=128
128 % 10 = 8
So 64519-22-8 is a valid CAS Registry Number.
64519-22-8Relevant academic research and scientific papers
An antiinflammatory active furochromone, norcimifugin from Cimicifuga foetida: Isolation, characterization, total synthesis and antiinflammatory activity of its Analogues
Lal, Bansi,Kansal,Singh, Rekha,Sankar,Kulkarni, Anagha S.,Gund, Vitthal G.
, p. 881 - 893 (2007/10/03)
In the course of our investigation to isolate the non-steroidal antiinflammatory active (NSAIA) lead molecules from the plants, 1 [(2S)-4-hydroxy-7-hydroxymethyl-2-(1-hydroxy-l-methylethyl)-2,3-dihydro-5H- oxolo[3′2′:4,5]-benzo [b]oxin-5-one also called as norcimifugin] has been isolated from the dichloromethane extract of rhizomes of Cimicifuga foetida. Characterization, total synthesis and antiinflammatory activity of 1 are reported. Alkyl, ester, carbamate, amine derivatives of 1 have been synthesized and their antiinflammatory activity assessed. Norcimifugin displayed antiinflammatory activity in the carrageenin induced paw edema model (50.4% inhibition at 50 mg/kg, p.o.).
