645393-95-9

Upstream product

• 133481-14-8 (2S)-2,3-O-isopropylidene-N-methoxy-N-methylpropanamide 
• 60456-21-5 methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 102045-96-5 2,3-O-isopropylidene-L-glyceric acid 

Downstream Products

• 645394-06-5 (1'R,2'R,4''R)-3-[1'-acryloyl-4'-(2'',2''-dimethyl-[1'',3'']dioxolan-4''-yl)-3'-methyl-2'-triethylsilanyloxymethylcyclohex-3'-enyl]propionitrile 
• 1027430-18-7 3-[(1R,2R)-4-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-methyl-2-triethylsilanyloxymethyl-1-((Z)-1-trimethylsilanyloxy-penta-1,4-dienyl)-cyclohex-3-enyl]-propionitrile 

Relevant academic research and scientific papers

Studies on the synthesis of (-)-gymnodimine. Subunit synthesis and coupling

Two principal subunits of the marine algal toxin (-)-gymnodimine were synthesized. A trisubstituted tetrahydrofuran representing C10-C18 of the toxin was prepared via a highly stereoselective iodine-mediated cyclization of an acyclic alkene bearing a bis-

Studies on the Synthesis of Gymnodimine. Construction of the Spiroimine Portion via Diels-Alder Cycloaddition

(Equation Presented) An azaspiro[5.5]undecadiene corresponding to a subunit of the shellfish toxin gymnodimine was synthesized by Diels-Alder cycloaddition. One member of the pair of stereoisomeric adducts was transformed to a spiroimine, which will serve